ArticleNucleic acids research2015
(PS)2: protein structure prediction server version 3.0.
Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed.
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- SeqCP: A sequence-based algorithm for searching circularly permuted proteins.Computational and structural biotechnology journal · 2023Article
- In Silico Methods for Identification of Potential Active Sites of Therapeutic Targets.Molecules (Basel, Switzerland) · 2022Review
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- Kunitz-Type Peptides from Sea Anemones Protect Neuronal Cells against Parkinson's Disease Inductors via Inhibition of ROS Production and ATP-Induced P2X7 Receptor Activation.International journal of molecular sciences · 2022Article
- Disulfiram blocked cell entry of SARS-CoV-2 via inhibiting the interaction of spike protein and ACE2.American journal of cancer research · 2022Article
- Functionalized Protein Nanotubes Based on the Bacteriophage vB_KleM-RaK2 Tail Sheath Protein.Nanomaterials (Basel, Switzerland) · 2021Article
- Effects of Distal Mutations on Ligand-Binding Affinity inACS omega · 2021Article
- CirPred, the first structure modeling and linker design system for circularly permuted proteins.BMC bioinformatics · 2021Article
- Role of juvenile hormone receptorZoological research · 2021Article
- Characterization of the Bubblegum acyl-CoA synthetase of Microchloropsis gaditana.Plant physiology · 2021Article
- The influence of dataset homology and a rigorous evaluation strategy on protein secondary structure prediction.PloS one · 2021Article
- A secondary structure-based position-specific scoring matrix applied to the improvement in protein secondary structure prediction.PloS one · 2021Article
- A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.Nature methods · 2020Article
- Monitoring the Heavy Metal Lead Inside Living Drosophila with a FRET-Based Biosensor.Sensors (Basel, Switzerland) · 2020Article
- A simple strategy to enhance the speed of protein secondary structure prediction without sacrificing accuracy.PloS one · 2020Article
- Computational Analysis ofCancer informatics · 2020Article
- Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition.Scientific reports · 2019Article
- Ensembles generated from crystal structures of single distant homologues solve challenging molecular-replacement cases in AMPLE.Acta crystallographica. Section D, Structural biology · 2018Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein complexes are involved in many biological processes. Examining coupling between subunits of a complex would be useful to understand the molecular basis of protein function. Here, our updated (PS)(2) web server predicts the three-dimensional structures of protein complexes based on comparative modeling; furthermore, this server examines the coupling between subunits of the predicted complex by combining structural and evolutionary considerations. The predicted complex structure could be indicated and visualized by Java-based 3D graphics viewers and the structural and evolutionary profiles are shown and compared chain-by-chain. For each subunit, considerations with or without the packing contribution of other subunits cause the differences in similarities between structural and evolutionary profiles, and these differences imply which form, complex or monomeric, is preferred in the biological condition for the subunit. We believe that the (PS)(2) server would be a useful tool for biologists who are interested not only in the structures of protein complexes but also in the coupling between subunits of the complexes. The (PS)(2) is freely available at http://ps2v3.life.nctu.edu.tw/.
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