ArticleNucleic acids research2015
FlyNet: a versatile network prioritization server for the Drosophila community.
Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Power spectrum curve compensation method for image quality enhancement in high-throughput gene sequencing.Biomedical optics express · 2025Article
- A curated tissue-specific proteome, phosphoproteome, and kinome map of Drosophila melanogaster with an integrated outlook in circadian physiology.Functional & integrative genomics · 2025Article
- Article
- BiomeNet: a database for construction and analysis of functional interaction networks for any species with a sequenced genome.Bioinformatics (Oxford, England) · 2020Article
- BarleyNet: A Network-Based Functional Omics Analysis Server for Cultivated Barley,Frontiers in plant science · 2020Article
- A Survey of Gene Prioritization Tools for Mendelian and Complex Human Diseases.Journal of integrative bioinformatics · 2019Review
- Predictability of Genetic Interactions from Functional Gene Modules.G3 (Bethesda, Md.) · 2017Article
- Enhancing gene regulatory network inference through data integration with markov random fields.Scientific reports · 2017Article
- SoyNet: a database of co-functional networks for soybean Glycine max.Nucleic acids research · 2017Article
- PoplarGene: poplar gene network and resource for mining functional information for genes from woody plants.Scientific reports · 2016Article
- MouseNet v2: a database of gene networks for studying the laboratory mouse and eight other model vertebrates.Nucleic acids research · 2016Article
Corrections and comments
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10 authors.
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Abstract
Drosophila melanogaster (fruit fly) has been a popular model organism in animal genetics due to the high accessibility of reverse-genetics tools. In addition, the close relationship between the Drosophila and human genomes rationalizes the use of Drosophila as an invertebrate model for human neurobiology and disease research. A platform technology for predicting candidate genes or functions would further enhance the usefulness of this long-established model organism for gene-to-phenotype mapping. Recently, the power of network prioritization for gene-to-phenotype mapping has been demonstrated in many organisms. Here we present a network prioritization server dedicated to Drosophila that covers ∼95% of the coding genome. This server, dubbed FlyNet, has several distinctive features, including (i) prioritization for both genes and functions; (ii) two complementary network algorithms: direct neighborhood and network diffusion; (iii) spatiotemporal-specific networks as an additional prioritization strategy for traits associated with a specific developmental stage or tissue and (iv) prioritization for human disease genes. FlyNet is expected to serve as a versatile hypothesis-generation platform for genes and functions in the study of basic animal genetics, developmental biology and human disease. FlyNet is available for free at http://www.inetbio.org/flynet.
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