Evidence map›Paper›PMID 25943543›Full record

ArticleNucleic acids research2015

TFmiR: a web server for constructing and analyzing disease-specific transcription factor and miRNA co-regulatory networks.

Mohamed Hamed, Christian Spaniol, Maryam Nazarieh, Volkhard Helms

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

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  5. MicroRNA Databases and Tools.Methods in molecular biology (Clifton, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohamed HamedCenter for Bioinformatics, Saarland University, 66041 Saarbrucken, Germany.
Christian SpaniolCenter for Bioinformatics, Saarland University, 66041 Saarbrucken, Germany.
Maryam NazariehCenter for Bioinformatics, Saarland University, 66041 Saarbrucken, Germany.
Volkhard HelmsCenter for Bioinformatics, Saarland University, 66041 Saarbrucken, Germany volkhard.helms@bioinformatik.uni-saarland.de.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TFmiR is a freely available web server for deep and integrative analysis of combinatorial regulatory interactions between transcription factors, microRNAs and target genes that are involved in disease pathogenesis. Since the inner workings of cells rely on the correct functioning of an enormously complex system of activating and repressing interactions that can be perturbed in many ways, TFmiR helps to better elucidate cellular mechanisms at the molecular level from a network perspective. The provided topological and functional analyses promote TFmiR as a reliable systems biology tool for researchers across the life science communities. TFmiR web server is accessible through the following URL: http://service.bioinformatik.uni-saarland.de/tfmir.

Indexed as

Gene Regulatory NetworksSoftwareBreast NeoplasmsDiseaseFemaleHumansInternetMicroRNAsTranscription FactorsMicroRNAsTranscription Factors

Identifiers

PMID25943543
PMCPMC4489273
OpenAlexW2113100102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.