Evidence map›Paper›PMID 25941574›Full record

ArticleOncoimmunology2014

B cells for cancer immunotherapy.

Jiusheng Deng, Jacques Galipeau

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jiusheng DengDepartment of Hematology and Medical Oncology; Winship Cancer Institute; Emory University ; Atlanta, GA USA.
Jacques GalipeauDepartment of Hematology and Medical Oncology; Winship Cancer Institute; Emory University ; Atlanta, GA USA ; Department of Pediatrics; Winship Cancer Institute; Emory University ; Atlanta, GA USA.
Piedmont Cancer Institute · USWinship Cancer Institute

Funding

Inducible B-regulatory cells (iBREGs) for treatment of Multiple SclerosisR01AI093881 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GALIPEAU, JACQUES · 2012 to 2016
$1.9M
NIAID NIH HHS R01 AI093881
6 · The paper itself

Abstract

We have engineered a novel fusion cytokine named GIFT4 derived from GM-CSF and IL-4, and displaying robust gain-of-function immunostimulatory effects on B cells. GIFT4-programmed B cells have a unique identity and potent capacity to elicit a tumoricidal - cell response, thus comprising a novel B cell-based cancer immunotherapeutic approach.

Indexed as

B cellscancer immunotherapyfusion cytokineGIFT4

Identifiers

PMID25941574
PMCPMC4292730
OpenAlexW2086351537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.