Evidence map›Paper›PMID 25941424›Full record

ArticleLaser therapy2015

Efficacy of LLLT in swelling and pain control after the extraction of lower impacted third molars.

Elisabetta Merigo, Paolo Vescovi, Meirav Margalit, Enrico Ricotti, Stefano Stea, Marco Meleti, Maddalena Manfredi, Carlo Fornaini

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Laser therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06150456 phase1completednot on this mapstarted 2022, after this paper: background citation

Evaluation of Alveolar Bone Preservation After Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.

TypeinterventionalSponsorUniversity of Nove de JulhoRan2022 to 2022Enrolled60ConditionsExtracting Own Teeth, Bone SubstitutesArmsextraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
NCT06164626 phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Evaluation of Alveolar Bone Preservation After Early Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.

TypeinterventionalSponsorUniversity of Nove de JulhoRan2023 to 2024Enrolled60ConditionsExtracting Own Teeth, Bone SubstitutesArmsExtraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  12. Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elisabetta MerigoUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Paolo VescoviUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Meirav MargalitUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Enrico RicottiUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Stefano SteaMaria Cecilia Hospital, Cotignola, Italy.
Marco MeletiUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Maddalena ManfrediUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
Carlo FornainiUnit of Oral Pathology, Medicine and Laser Surgery, Department of Biomedical, Biotechnological and Translational Sciences (S.Bi.Bi.T), University of Parma, Italy.
University of Parma · ITMaria Cecilia Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimLow Level Laser Therapy (LLLT) can facilitate wound healing stimulating a more rapid resolution and an earlier start for the proliferation phase. The purpose of this study is to evaluate the effects of LLLT on postoperative pain and oedema following the removal of impacted lower third molars. MATERIALS AND

methodsFifty-nine patients, who were to undergo surgical removal of their lower third molars, were studied. Patients were randomly allocated to one of three groups: 17 patients LLLT + traditional drug treatment17 patients traditional drug treatment as control group25 patients treated with LLLT only on one side+traditional drug treatment. The laser we have used for this study is a diode laser, GaAs, which delivers both in the infrared band at the wavelength of 910 nanometers (pulsed and superpulsed source), and in the visible (continuous source) at the wavelength of 650 nanometers (red). LLLT was performed just after the intervention and approximately 12 hours after surgery delivering 240 J in 15 minutes with theoretical fluence values of 480 J/cm(2) and 31 J/cm(2) for every minute of irradiation. We considered and signed with a label constant landmarks on both sides of the face of each patient; measurements were taken: before the surgery, after the surgery right after the 1st laser treatment, after approximately 24 hours after the 2(nd) laser treatment.

resultsWe collected all the values of the oedema measurements and the VAS reports and performed a statistical analysis by means One-way Analysis of Variance (ANOVA) test: for the evaluated values (X, Y, Z) an extremely significant difference was found with p values of 0.003 for Y at the first evaluation (pre-12 hours) and less than 0.001 for the other evaluations. A significant result was obtained for VAS recorded at hospital discharge (p<0.0001).

conclusionsThis study demonstrates that LLLT is effective on postoperative pain and oedema accelerating healing time and reducing patients distress.

Indexed as

extractionLLLT; PainLower third molarsLow Level Laser TherapyQuality of life

Identifiers

PMID25941424
PMCPMC4416144
OpenAlexW2013428084

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.