Evidence map›Paper›PMID 25941301›Full record

ArticlePediatrics2015

The pharmacy-level asthma medication ratio and population health.

Andrew F Beck, Courtney L Bradley, Bin Huang, Jeffrey M Simmons, Pamela C Heaton, Robert S Kahn

Abstract read
In one paragraph

Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Identifying which children with persistent asthma have preventive medications available at home.The Journal of asthma : official journal of the Association for the Care of Asthma · 2020
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. A missed primary care appointment correlates with a subsequent emergency department visit among children with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Andrew F BeckDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; andrew.beck1@cchmc.org.
Courtney L BradleyUniversity of North Carolina School of Pharmacy, Chapel Hill, North Carolina; Kroger Pharmacy, Cincinnati, Ohio; and University of Cincinnati College of Pharmacy, Cincinnati, Ohio.
Bin HuangDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;
Jeffrey M SimmonsDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;
Pamela C HeatonUniversity of Cincinnati College of Pharmacy, Cincinnati, Ohio.
Robert S KahnDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;

Funding

Inpatient Asthma Care for Children: Adding a Place-Based, Community-Focused ApproK23AI112916 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI BECK, ANDREW FINKEL · 2014 to 2018
$721k
NIAID NIH HHS 1K23AI112916NIAID NIH HHS K23 AI112916
6 · The paper itself

Abstract

BACKGROUND AND

objectivesCommunity pharmacies may be positioned for an increased role in population health. We sought to develop a population-level measure of asthma medication fills and assess its relationship to asthma-related utilization.

methodsWe conducted a retrospective, ecological study (2010-2012). Medication data from a chain of pharmacies (n = 27) within 1 county were used to calculate a Pharmacy-level Asthma Medication Ratio (Ph-AMR), defined as controller fills divided by controller plus rescue fills. Higher values are superior because they indicate more controller compared with rescue fills. The outcome was the asthma-related utilization rate among children in the same census tract as the pharmacy, calculated by dividing all emergency visits and hospitalizations by the number of children in that tract. Covariates, including ecological measures of poverty and access to care, were used in multivariable linear regression.

resultsOverall, 35 467 medications were filled. The median Ph-AMR was 0.53 (range 0.38-0.66). The median utilization rate across included census tracts was 22.4 visits per 1000 child-years (range 1.3-60.9). Tracts with Ph-AMR <0.5 had significantly higher utilization rates than those with Ph-AMR ≥0.5 (26.1 vs 9.9; P = .001). For every 0.1 increase in Ph-AMR, utilization rates decreased by 9.5 (P = .03), after adjustment for underlying poverty and access. Seasonal variation in fills was evident, but pharmacies in high-utilizing tracts filled more rescue than controller medications at nearly every point during the study period.

conclusionsPh-AMR was independently associated with ecological childhood asthma morbidity. Pharmacies may be a community-based leverage point for improving population-level asthma control through targeted interventions.

Indexed as

Anti-Asthmatic AgentsAsthmaChildChild, PreschoolDrug PrescriptionsFemaleHealth StatusHumansMalePharmaceutical ServicesRetrospective StudiesAnti-Asthmatic Agents

Identifiers

PMID25941301
PMCPMC4444803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.