Evidence map›Paper›PMID 25941178›Full record

ArticleBMJ open2015

Acute Care QUAliTy in chronic Kidney disease (ACQUATIK): a prospective cohort study exploring outcomes of patients with chronic kidney disease.

Julia J Arnold, Manvir Hayer, Adnan Sharif, Irena Begaj, Mohammed Tabriez, David Bagnall, Daniel Ray, Ciaron Hoye, Masood Nazir, Mary Dutton and 8 more

Abstract read
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Julia J ArnoldDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Manvir HayerDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Adnan SharifDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Irena BegajDepartment of Informatics, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Mohammed TabriezDepartment of Informatics, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
David BagnallDepartment of Informatics, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Daniel RayDepartment of Informatics, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Ciaron HoyeBirmingham Crosscity Clinical Commissioning Group, Birmingham, UK.
Masood NazirBirmingham Crosscity Clinical Commissioning Group, Birmingham, UK.
Mary DuttonDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Lesley FiferDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Katie KirkhamDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Don SimsCare of the Elderly Medicine, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Jonathan N TownendDepartment of Cardiology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Paramjit S GillPrimary Care Clinical Sciences, University of Birmingham, Birmingham, UK.
Indranil DasguptaDepartment of Nephrology, Heart of England NHS Foundation Trust and University of Birmingham, Birmingham, UK.
Paul CockwellDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.
Charles J FerroDepartment of Nephrology, Queen Elizabeth Hospital and University of Birmingham, Birmingham, UK.

Funding

Department of Health PDF-2012-05-205
6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) is common and carries a high risk of morbidity, including hospital admissions and readmissions and mortality. This is largely attributed to an increased risk of cardiovascular disease. Patients with CKD are less likely to receive evidence-based treatments for cardiovascular disease. However, these treatments are based on trials which generally exclude patients with CKD. It is therefore unclear whether this patient group derives the same benefits without an increased risk of adverse effects. METHODS AND ANALYSIS: The Acute Care QUAliTy in chronic Kidney disease (ACQUATIK) study is a prospective, observational, multicentre cohort study. Over 4000 patients will be recruited with an enrolment period of 2 years and a follow-up period of 2-4 years. Patients under follow-up by a renal team will be excluded. Data will be obtained from patient and hospital records during the index admission. Preadmission data will be extracted from general practice records based on the Quality and Outcomes Framework. Diagnosis, comorbidities and procedure data pertaining to the index and subsequent admissions will be extracted from the Hospital Episode Statistics database and long-term mortality data will be tracked using the Office of National Statistics. This information will allow us to examine a complete patient journey through primary and secondary care, providing unequalled levels of information on treatment and outcomes of patients with CKD. The combined data set will be used to compare outcomes and treatments among patients with CKD versus patients without CKD. The primary end point is hospital readmission rates. The relationship between age, sex, ethnicity, socioeconomic status and concurrent comorbidities will be analysed to determine their influence on outcomes and treatments. ETHICS AND DISSEMINATION: The ACQUATIK study has been approved by the NRES Committee West Midlands-South Birmingham-Reference 13/WM/0317. The results from ACQUATIK will be submitted for publication in peer-reviewed journals and presented at primary and secondary care conferences. TRIAL REGISTRATION NUMBER: ISRCTN37237454.

Indexed as

Outcome Assessment, Health CarePatient ReadmissionAdolescentAdultCardiovascular DiseasesComorbidityFemaleHumansKidneyKidney Failure, ChronicMalePatient SelectionPrimary Health CareProspective StudiesRenal Insufficiency, ChronicResearch DesignPRIMARY CARE

Identifiers

PMID25941178
PMCPMC4420952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.