Evidence map›Paper›PMID 25941075›Full record

ArticleMolecular neurobiology2016

Distinct Hippocampal Expression Profiles of lncRNAs in Rats Exhibiting a PTSD-like Syndrome.

Liu Qingzhen, Ma Jiehua, Yu Zhiyang, Liu Hongjun, Chen Chunlong, Li Weiyan

Abstract read
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Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. The role of long noncoding RNA in traumatic brain injury.Neuropsychiatric disease and treatment · 2019
    Review
  8. Article
  9. Neuroepigenetics of Post-Traumatic Stress Disorder.Progress in molecular biology and translational science · 2018
    Review
  10. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liu QingzhenDepartment of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China.
Ma JiehuaDepartment of Reproductive Health, State Key Laboratory of Reproductive Medicine, Nanjing Maternity and Child Health Care Hospital of Nanjing Medical University, Nanjing, 210004, China.
Yu ZhiyangDepartment of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China.
Liu HongjunDepartment of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China.
Chen ChunlongDepartment of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China.
Li WeiyanDepartment of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China. liweiyan198211@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) refers to a series of clinical syndromes, including symptoms such as nightmares, hallucinations, severe anxiety, fear, and trauma related to the environment. These symptoms tend to occur after intense psychological trauma or physiological stress. Long non-coding RNAs (lncRNAs) have been shown to play key roles in various biological processes, although it is unknown whether they have important functions in PTSD. Here, we present the first study exploring the connection between lncRNAs and a PTSD-like syndrome in rats. We find distinct expression profiles of lncRNAs between PTSD-like syndrome rats and a control group, which provides information for further research on the differentiation of PTSD and transdifferentiation between the PTSD-like syndrome and the control group. This information will be helpful for finding new therapeutic targets for the treatment of PTSD.

Indexed as

Gene Expression ProfilingGene Expression RegulationAnimalsBehavior, AnimalFreezing Reaction, CatalepticGene OntologyHippocampusMaleOligonucleotide Array Sequence AnalysisRats, Sprague-DawleyReal-Time Polymerase Chain ReactionRNA, Long NoncodingRNA, MessengerStress Disorders, Post-TraumaticRNA, Long NoncodingRNA, MessengerHippocampusLong non-coding RNAs (lncRNAs)MicroarrayPTSD

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.