ReviewNature reviews. Nephrology2015
Long-term medical risks to the living kidney donor.
Review in Nature reviews. Nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Research hotspots and future trends in lipid metabolism in chronic kidney disease: a bibliometric and visualization analysis from 2004 to 2023.Frontiers in pharmacology · 2024Pooled it
- Long-term mortality of living kidney donors: a systematic review and meta-analysis.International urology and nephrology · 2021Pooled it
- KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors.Transplantation · 2017Guideline
- Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate.The New England journal of medicine · 2016Pooled it
- Long-Term Outcomes of Living Kidney Donors Left with Multiple Renal Arteries: A Retrospective Cohort Study from a Single Center.Journal of clinical medicine · 2025Article
- Pregnancy in Living Kidney Donors: An Evidence-Based Review.Current transplantation reports · 2023Article
- Article
- Living kidney donation in a developing country.PloS one · 2022Article
- Long-term renal function in living kidney donors with simple renal cysts: A retrospective cohort study.Clinical transplantation · 2020Article
- Long-term compensation of renal function after donor nephrectomy.Korean journal of transplantation · 2020Article
- Canadian Society of Transplantation and Canadian Society of Nephrology Commentary on the 2017 KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors.Canadian journal of kidney health and disease · 2020Article
- Removing Disincentives to Kidney Donation: A Quantitative Analysis.Journal of the American Society of Nephrology : JASN · 2019Article
- Low Birth Weight, Blood Pressure and Renal Susceptibility.Current hypertension reports · 2019Review
- Health Professional-Identified Barriers to Living Donor Kidney Transplantation: A Qualitative Study.Canadian journal of kidney health and disease · 2019Article
- Mood, body image, fear of kidney failure, life satisfaction, and decisional stability following living kidney donation: Findings from the KDOC study.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018Article
- Follow-up Care of Living Kidney Donors in Alberta, Canada.Canadian journal of kidney health and disease · 2018Article
- Summary of Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors.Transplantation · 2017Review
- Renal and cardiac assessment of living kidney donor candidates.Nature reviews. Nephrology · 2017Review
- Does significant renal ablation truly and invariably lead to hyperfiltration and progressive chronic kidney disease?Clinical and experimental nephrology · 2017Review
- Continuous Normothermic Ex Vivo Kidney Perfusion Improves Graft Function in Donation After Circulatory Death Pig Kidney Transplantation.Transplantation · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Living kidney donation benefits recipients and society but carries short-term and long-term risks for the donor. This Review summarizes the studies that underlie our current understanding of these risks in the first decade after donation, with a view to improving the informed consent process. Two studies report a higher risk of end-stage renal disease (ESRD) among donors than among healthy nondonors; however, the absolute 15-year incidence of ESRD is <1%. All-cause mortality and the risk of cardiovascular events are similar among donors and healthy nondonors, although one study provides evidence for a 5% increase in all-cause mortality after 25 years that is attributable to donation. Some evidence suggests that the 20-year incidence of gout is slightly higher among donors than among healthy nondonors. The risks of gestational hypertension or pre-eclampsia seem to be 6% higher in pregnancies among donors than in pregnancies among healthy nondonors. The incidences of acute kidney injury, kidney stones that require surgical intervention, gastrointestinal bleeding and fractures seem no higher among donors than among healthy nondonors, although some of these conclusions are based on a small number of events. Future studies must clarify the lifetime incidence of long-term outcomes, particularly in relation to a donor's age, race, and history of comorbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.