ArticleTropical medicine & international health : TM & IH2015
Cysticercosis and epilepsy in rural Tanzania: a community-based case-control and imaging study.
Article in Tropical medicine & international health : TM & IH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- The epidemiology of human Taenia solium infections: A systematic review of the distribution in Eastern and Southern Africa.PLoS neglected tropical diseases · 2023Pooled it
- The causal relationship between neurocysticercosis infection and the development of epilepsy - a systematic review.Infectious diseases of poverty · 2017Pooled it
- Prevalence of neurocysticercosis and its characteristics among people with epileptic seizures and progressively worsening severe headaches in 60 villages in three provinces of Burkina Faso.PLoS neglected tropical diseases · 2026Trial
- Knowledge, attitudes, and practices towards prevention and control of neurocysticercosis-related epilepsy in Northern Tanzania: A cross-sectional healthcare professional-based study.PLoS neglected tropical diseases · 2025Article
- The hidden threat of cysticercosis: A neglected public health problem.Open veterinary journal · 2025Review
- Integration of onchocerciasis morbidity management and disability prevention services in the healthcare system in Tanzania: a call for action and recommendations.Tropical diseases, travel medicine and vaccines · 2024Article
- Knowledge, attitudes and practices related to Taenia solium cysticercosis and taeniasis in Tanzania.BMC infectious diseases · 2022Article
- Prevalence of Epilepsy, Human Cysticercosis, and Porcine Cysticercosis in Western Kenya.The American journal of tropical medicine and hygiene · 2022Article
- CystiHuman: A model of human neurocysticercosis.PLoS computational biology · 2022Article
- Article
- Taenia solium cysticercosis and taeniasis in urban settings: Epidemiological evidence from a health-center based study among people with epilepsy in Dar es Salaam, Tanzania.PLoS neglected tropical diseases · 2019Article
- Article
- Animal influence on water, sanitation and hygiene measures for zoonosis control at the household level: A systematic literature review.PLoS neglected tropical diseases · 2018Review
- Article
- Burden of neurodevelopmental disorders in low and middle-income countries: A systematic review and meta-analysis.Wellcome open research · 2017Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 3 countries.
Funding
Abstract
objectiveTo assess the contribution of neurocysticercosis (NCC) to the burden of epilepsy in a rural Tanzanian population.
methodsWe identified adult people with epilepsy (PWE) in a door-to-door study in an established demographic surveillance site. PWE and community controls were tested for antibodies to Taenia solium, the causative agent of NCC, and all PWE were offered a computed tomography (CT) head scan. Data on household occupancy and sanitation, pig-keeping and pork consumption were collected from PWE and controls and associations with epilepsy were assessed using chi-square or Fisher's exact tests.
resultsSix of 218 PWE had antibodies to T. solium (2.8%; 95% CI 0.6-4.9), compared to none of 174 controls (Fisher's exact test, P = 0.04). Lesions compatible with NCC were seen in eight of 200 CT scans (4.0%; 95% CI 1.3-6.7). A total of 176 PWE had both investigations of whom two had positive serology along with NCC-compatible lesions on CT (1.1%; 95% 0.3-4.0). No associations between epilepsy and any risk factors for NCC were identified.
conclusionsNeurocysticercosis is present in this population but at a lower prevalence than elsewhere in Tanzania and sub-Saharan Africa. Insights from low-prevalence areas may inform public health interventions designed to reduce the burden of preventable epilepsy.
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Registered trials
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