Evidence map›Paper›PMID 25940725›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2015

International Pediatric Non-Hodgkin Lymphoma Response Criteria.

John T Sandlund, R Paul Guillerman, Sherrie L Perkins, C Ross Pinkerton, Angelo Rosolen, Catherine Patte, Alfred Reiter, Mitchell S Cairo

Registry-linked trialAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05681260 (A Randomized Trial Using a Modified COG ABFM Regimen Backbone to Investigate Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05681260 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

A Randomized Trial Using a Modified COG ABFM Regimen Backbone to Investigate Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL)

TypeinterventionalSponsorChildren's Cancer Group, ChinaRan2023 to 2029Enrolled200ConditionsT-cell Lymphoblastic LymphomaArmsPrednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin, Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin, Vindesine, Etoposide, Ifosfamide
3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
    Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Clinical Perspectives forMetabolites · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

John T SandlundJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
R Paul GuillermanJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
Sherrie L PerkinsJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
C Ross PinkertonJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
Angelo RosolenJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
Catherine PatteJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
Alfred ReiterJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY.
Mitchell S CairoJohn T. Sandlund, St Jude Children's Research Hospital, Memphis, TN; R. Paul Guillerman, Texas Children's Hospital, Houston, TX; Sherrie L. Perkins, University of Utah Health Sciences Center, Salt Lake City, UT; C. Ross Pinkerton, University of Queensland, Brisbane, Queensland, Australia; Angelo Rosolen, University of Padova, Padova, Italy; Catherine Patte, Institut Gustave Roussy, Paris, France; Alfred Reiter, Justus-Liebig-University of Giessen, Giessen, Germany; and Mitchell S. Cairo, New York Medical College, Valhalla, NY. mitchell_cairo@nymc.edu.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Fourth International Symposium on Childhood, Adolescent and Young Adult Non-HodgkR13CA171748 · NCI · NEW YORK MEDICAL COLLEGE · PI CAIRO, MITCHELL S. · 2012 to 2012
$15k
NCI NIH HHS 1R13CA171748-01NCI NIH HHS CA 21765NCI NIH HHS P30 CA021765NCI NIH HHS R13 CA171748
6 · The paper itself

Abstract

purposeResponse criteria are well established for adult patients with non-Hodgkin lymphoma (NHL). A revised set of response criteria in adults with NHL was recently published. However, NHL in children and adolescents involves different histologies, primary sites of disease, patterns of metastatic spread, approaches to therapy, and responses to treatment compared with adult NHL. However, there are no standardized response criteria specific to pediatric NHL. Therefore, we developed international standardized methods for assessing response to therapy in children and adolescents with NHL.

methodsAn international multidisciplinary group of pediatric oncologists, pathologists, biologists, and radiologists convened during and after the Third and Fourth International Childhood, Adolescent and Young Adult NHL Symposia to review existing response and outcome data, develop methods for response evaluation that reflect incorporation of more sensitive technologies currently in use, and incorporate primary and metastatic sites of disease for the evaluation of therapeutic response in children and adolescents with NHL.

resultsUsing the current adult NHL response criteria as a starting point, international pediatric NHL response criteria were developed incorporating both contemporary diagnostic imaging and pathology techniques, including novel molecular and flow cytometric technologies used for the determination of minimal residual disease.

conclusionUse of the international pediatric NHL response criteria in children and adolescents receiving therapy for NHL incorporates data obtained from new and more sensitive technologies that are now being widely used for disease evaluation, providing a standardized means for reporting treatment response.

Indexed as

HumansLymphoma, Non-HodgkinNeoplasm Staging

Identifiers

PMID25940725
PMCPMC4461807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.