Evidence map›Paper›PMID 25940578›Full record

ArticleBMC musculoskeletal disorders2015

Productivity at work and quality of life in patients with rheumatoid arthritis.

Myrthe van Vilsteren, Cecile R L Boot, Dirk L Knol, Dirkjan van Schaardenburg, Alexandre E Voskuyl, Romy Steenbeek, Johannes R Anema

Registry-linked trialAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06480643 (Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06480643 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA: an Explorative Study The Care for Muscle Study

TypeinterventionalSponsorAmsterdam UMC, location VUmcRan2024 to 2027Enrolled69ConditionsRheumatoid Arthritis, Osteoarthritis, SarcopeniaArmsHigh load exercise type, Low load exercise type
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. Work Ability and Quality of Life in Patients with Rheumatoid Arthritis.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myrthe van VilsterenDepartment of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. m.vanvilsteren@vumc.nl.
Cecile R L BootDepartment of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. crl.boot@vumc.nl.
Dirk L KnolDepartment of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. d.knol@vumc.nl.
Dirkjan van SchaardenburgJan van Breemen Research Institute Reade, Amsterdam, the Netherlands. d.v.schaardenburg@reade.nl.
Alexandre E VoskuylDepartment of Rheumatology, VU University Medical Center, Amsterdam, the Netherlands. ae.voskuyl@vumc.nl.
Romy SteenbeekBody@Work, Research Center Physical Activity, TNO-VU University Medical Center, Amsterdam, the Netherlands. romy.steenbeek@tno.nl.
Johannes R AnemaDepartment of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. h.anema@vumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine which combination of personal, disease-related and environmental factors is best associated with at-work productivity loss in patients with rheumatoid arthritis (RA), and to determine whether at-work productivity loss is associated with the quality of life for these patients.

methodsThis study is based on cross-sectional data. Patients completed a questionnaire with personal, disease-related and environmental factors (related to the work environment), and clinical characteristics were obtained from patient medical records. At-work productivity loss was measured with the Work Limitations Questionnaire, and quality of life with the RAND 36. Using linear regression analyses, a multivariate model was built containing the combination of factors best associated with at-work productivity loss. This model was cross-validated internally. We furthermore determined whether at-work productivity loss was associated with quality of life using linear regression analyses.

resultsWe found that at-work productivity loss was associated with workers who had poorer mental health, more physical role limitations, were ever treated with a biological therapeutic medication, were not satisfied with their work, and had more work instability (R(2) = 0.50 and R(2) following cross-validation was 0.32). We found that at-work productivity loss was negatively associated with health-related quality of life, especially with dimensions of mental health, physical role limitations, and pain.

conclusionsWe found that at-work productivity loss was associated with personal, work-related, and clinical factors. Although our study results should be interpreted with caution, they provide insight into patients with RA who are at risk for at-work productivity loss.

Indexed as

AdultAgedArthritis, RheumatoidCross-Sectional StudiesEfficiencyEnvironmentFemaleHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisQuality of LifeRandomized Controlled Trials as TopicRisk FactorsSick Leave

Identifiers

PMID25940578
PMCPMC4425924

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.