ArticleEnvironmental science and pollution research international2015
Preliminary evaluation of Diopatra neapolitana regenerative capacity as a biomarker for paracetamol exposure.
Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Assessment of Paracetamol Toxic Effects under Varying Seawater pH Conditions on the Marine PolychaeteBiology · 2022Article
- Studying Annelida Body Regeneration Under Environmental Stress in Diopatra neapolitana.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Comparative biomarker responses to urban pollution in three polychaete species: Perinereis cultrifera, Diopatra neapolitana, and Marphysa sanguinea from the lagoon of Tunis.Environmental monitoring and assessment · 2021Article
- Effect of Acetaminophen (APAP) on Physiological Indicators inLife (Basel, Switzerland) · 2020Article
- Effects of commonly used therapeutic drugs, paracetamol, and acetylsalicylic acid, on key physiological traits of the sea snail Gibbula umbilicalis.Environmental science and pollution research international · 2019Article
- Worms on drugs: ecotoxicological effects of acetylsalicylic acid on the Polychaeta species Hediste diversicolor in terms of biochemical and histological alterations.Environmental science and pollution research international · 2019Article
- Effects of acetaminophen in oxidative stress and neurotoxicity biomarkers of the gastropod Phorcus lineatus.Environmental science and pollution research international · 2019Article
- Organic micropollutants paracetamol and ibuprofen-toxicity, biodegradation, and genetic background of their utilization by bacteria.Environmental science and pollution research international · 2018Review
- Cholinesterase characterization of two autochthonous species of Ria de Aveiro (Diopatra neapolitana and Solen marginatus) and comparison of sensitivities towards a series of common contaminants.Environmental science and pollution research international · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of studies established unequivocal relationships between exposure to pharmaceutical drugs and toxicity in wildlife. However, few studies investigated physiological alterations caused by such compounds in polychaetes. Thus, in this study, the effects of increasing concentrations of paracetamol were studied in the polychaete Diopatra neapolitana using tissue regenerative capacity as a biomarker. The obtained results revealed that individuals exposed to ecologically relevant concentrations (namely, 25 μg/L) of paracetamol exhibited significantly lower capacity to regenerate their body in comparison with control organisms. This study evidenced that paracetamol can induce significant physiological alterations in D. neapolitana resulting in an overall diminished regenerative capacity, which is of significance to a species with high ecological and economic relevance. Additionally, this study indicates the promise of D. neapolitana as a test organism in laboratory-based bioassays, but also as an adequate sentinel species to pharmaceutical drugs.
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