ArticleCurrent infectious disease reports2015
Sepsis in the severely immunocompromised patient.
Article in Current infectious disease reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
- Immunosuppression Masking a Urological Emergency: A Case Report of Bilateral Infected Obstructed Kidneys.Cureus · 2025Article
- Eravacycline use in immunocompromised patients: multicenter evaluation of timely versus late initiation on clinical outcomes.Microbiology spectrum · 2025Observational
- National emergency department trends for endogenous endophthalmitis: an increasing public health challenge.Eye (London, England) · 2023Article
- Clinical Outcomes and Risk Factors for Death following Carbapenem-Resistant Klebsiella pneumoniae Infection in Solid Organ Transplant Recipients.Microbiology spectrum · 2023Article
- Development and Assessment of a Novel Predictive Nomogram to Predict the Risk of Secondary CR-GNB Bloodstream Infections among CR-GNB Carriers in the Gastroenterology Department: A Retrospective Case-Control Study.Journal of clinical medicine · 2023Article
- Prognostic Impact of Neutropenia in Cancer Patients with Septic Shock: A 2009-2017 Nationwide Cohort Study.Cancers · 2022Article
- Impact of Early Pancreatic Graft Loss on Outcome after Simultaneous Pancreas-Kidney Transplantation (SPKT)-A Landmark Analysis.Journal of clinical medicine · 2021Article
- Bioinformatics Analysis for Identifying Pertinent Pathways and Genes in Sepsis.Computational and mathematical methods in medicine · 2021Article
- Presenting Symptoms in Sepsis: Is the Mnemonic "SEPSIS" Useful?Infection and drug resistance · 2020Article
- Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients.Intensive care medicine · 2019Review
- Characterization of Pathogenic Sepsis Etiologies and Patient Profiles: A Novel Approach to Triage and Treatment.Microbiology insights · 2019Review
- IL-17, IL-27, and IL-33: A Novel Axis Linked to Immunological Dysfunction During Sepsis.Frontiers in immunology · 2019Review
- Infectious Complications Following Solid Organ Transplantation.Critical care clinics · 2019Review
- Epidemiology and Immune Pathogenesis of Viral Sepsis.Frontiers in immunology · 2018Review
- Inpatient Mortality Among Solid Organ Transplant Recipients Hospitalized for Sepsis and Severe Sepsis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Article
- Rhodiola rosea suppresses thymus T-lymphocyte apoptosis by downregulating tumor necrosis factor-α-induced protein 8-like-2 in septic rats.International journal of molecular medicine · 2015Article
- Immunosuppression in Liver Transplant Recipients in the Setting of Sepsis.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevention and treatment of sepsis in the immunocompromised host present a challenging array of diagnostic and management issues. The neutropenic patient has a primary defect in innate immune responses and is susceptible to conventional and opportunistic pathogens. The solid organ transplant patient has a primary defect in adaptive immunity and is susceptible to a myriad of pathogens that require an effective cellular immune response. Risk for infections in organ transplant recipients is further complicated by mechanical, vascular, and rejection of the transplanted organ itself. The immune suppressed state can modify the cardinal signs of inflammation, making accurate and rapid diagnosis of infection and sepsis difficult. Empiric antimicrobial agents can be lifesaving in these patients, but managing therapy in an era of progressive antibiotic resistance has become a real issue. This review discusses the challenges faced when treating severe infections in these high-risk patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.