Trial reportProstate cancer and prostatic diseases2015
Acupuncture relieves symptoms in chronic prostatitis/chronic pelvic pain syndrome: a randomized, sham-controlled trial.
Trial report in Prostate cancer and prostatic diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 8 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Acupuncture for Chronic Prostatitis or Chronic Pelvic Pain Syndrome: An Updated Systematic Review and Meta-Analysis.Pain research & management · 2023Pooled it
- Comparative efficacy of acupuncture-related therapy for migraine: A systematic review and network meta-analysis.Frontiers in neurology · 2022Pooled it
- Traditional Chinese medicine on treating chronic prostatitis/chronic pelvic pain syndrome: A systematic review and meta-analysis.Medicine · 2019Pooled it
- Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome.The Cochrane database of systematic reviews · 2018Pooled it
- Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome.The Cochrane database of systematic reviews · 2018Pooled it
- Effect of acupuncture on clinical symptoms and laboratory indicators for chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis.International urology and nephrology · 2016Pooled it
- Systematic Review of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome.Medicine · 2016Pooled it
- Evaluation of Clinical Effect of Acupuncture on Chronic Prostatitis: Meta Analysis.American journal of men's healthPooled it
- Effectiveness and Safety of Umbilicus Treatment with Modified Dinggui Powder () in Patients with Chronic Nonbacterial Prostatitis: A Randomized, Double-blind, Placebo-controlled Clinical Trial.Chinese journal of integrative medicine · 2021Trial
- Trial
- Efficacy of acupuncture for chronic prostatitis/chronic pelvic pain syndromes: study protocol for a randomized, sham acupuncture-controlled trial.BMC complementary and alternative medicine · 2016Trial
- Review
- Potential mechanisms of acupuncture in regulating neuroinflammation and central sensitization in chronic pain: a narrative review of preclinical, clinical, and translational evidence.American journal of translational research · 2026Review
- Acupuncture's Multisystem Neuroimmunomodulation: Central-Peripheral Interactions in Gastroenteric, Psychiatric, and Chronic Pain Disorders.CNS neuroscience & therapeutics · 2025Review
- Efficacy of Different Acupuncture Therapies for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Network Meta-Analysis.Journal of pain research · 2025Review
- Electroacupuncture for Refractory Chronic Pelvic Pain: A Case Report with 24-Month Follow-Up.International journal of women's health · 2025Article
- The role of acupuncture in treating premature ejaculation and its probable neurobiological mechanism.Basic and clinical andrology · 2024Review
- Chronic Primary Pelvic Pain Syndrome in Men.Deutsches Arzteblatt international · 2023Review
- Analgesic Efficacy of Acupuncture on Chronic Pelvic Pain: A Systemic Review and Meta-Analysis Study.Healthcare (Basel, Switzerland) · 2023Review
- Research Trends of Acupuncture Therapy on Chronic Pelvic Pain Syndrome from 2000 to 2022: A Bibliometric Analysis.Journal of pain research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are multiple approaches to the management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS); and lately the data suggesting the ability of acupuncture treatment to decrease pain, positively impact quality of life and potentially modulate inflammation has suggested it as a potential therapeutic option for men with CP/CPPS. We conducted this study to determine whether acupuncture is really an effective therapeutic modality for CP/CPPS in terms of >50% decrease in total National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) score from baseline compared with sham.
methodsOne hundred patients with CP/CPPS (category III B) in an outpatient urology clinic were randomized to receive acupuncture at either seven acupoints bilaterally or sham points adjacent to these points. NIH-CPSI was completed by each patient before and 6, 8, 16, 24 weeks after the treatment. Mean values of total CPSI score and subscores after the treatment and on follow-up following the treatment were compared.
resultsOf the acupuncture participants, 92% were NIH-CPSI responders (>50% decrease in total NIH-CPSI score from baseline) compared with 48% of sham participants, 8 weeks after the end of the therapy. Both groups experienced significant decrease in CPSI subscores throughout the whole follow-up period; however, the decline remained significantly greater in the active acupuncture group as compared with the sham group.
conclusionsOur results show that the use of acupuncture in treatment of men with CP/CPPS symptoms resulted in a significant decrease in total NIH-CPSI scores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.