Evidence map›Paper›PMID 25939394›Full record

Trial reportPublic health nutrition2016

Recovery rate of children with moderate acute malnutrition treated with ready-to-use supplementary food (RUSF) or improved corn-soya blend (CSB+): a randomized controlled trial.

Gabriel Nama Medoua, Patricia M Ntsama, Anne Christine A Ndzana, Véronique J Essa'a, Julie Judith T Tsafack, Henriette T Dimodi

Registry-linked trialOpen access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Public health nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06792370 (Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition in Children Aged 6-59 Months in Burkina Faso), which is not on this map. Cited by 24 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 6 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06792370 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition in Children Aged 6-59 Months in Burkina Faso: Reduced Dose of RUTF for SAM Children and RUTF Instead of RUSF for MAM Children

TypeinterventionalSponsorInstitut de Recherche en Sciences de la Sante, Burkina FasoRan2025 to 2026Enrolled3,521ConditionsAcute Malnutrition with No ComplicationsArmsready-to-use therapeutic food (for children with MAM), Ready-to-use supplementary food, Ready to Use Therapeutic Food - Reduced dose 1, Ready to Use Therapeutic Food - Standard dose, Ready to Use Therapeutic Food - Reduced dose 2
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gabriel Nama MedouaCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Patricia M NtsamaCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Anne Christine A NdzanaCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Véronique J Essa'aCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Julie Judith T TsafackCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Henriette T DimodiCentre for Food and Nutrition Research,Institute of Medical Research and Medicinal Plants Studies (IMPM),PO Box 6163,Yaoundé,Cameroon.
Institut de Recherches Médicales et d’Etudes des Plantes Médicinales · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare an improved corn-soya blend (CSB+) with a ready-to-use supplementary food (RUSF) to test the hypothesis that satisfactory recovery rate will be achieved with CSB+ or RUSF when these foods provide 50 % of the child's energy requirement, the 50 % remaining coming from usual diet.

designA comparative efficacy trial study was conducted with moderately wasted children, using a controlled randomized design, with parallel assignment for RUSF or CSB+. Every child received a daily ration of 167 kJ (40 kcal)/kg body weight during 56 d with a follow-up performed every 14 d. Every caregiver received nutrition counselling at enrolment and at each follow-up visit.

settingHealth districts of Mvog-Beti and Evodoula in the Centre region of Cameroon. SUBJECTS: Eight hundred and thirty-three children aged 6-59 months were screened and eighty-one malnourished children (weight-for-height Z-score between -3 and -2) aged 25-59 months were selected.

resultsOf children treated with CSB+ and RUSF, 73 % (95 % CI 59 %, 87 %) and 85 % (95 % CI 73 %, 97 %), respectively, recovered from moderate acute malnutrition, with no significant difference between groups. The mean duration of treatment required to achieve recovery was 44 d in the RUSF group and 51 d in the CSB+ group (log-rank test, P=0·0048).

conclusionsThere was no significant difference in recovery rate between the groups. Both CSB+ and RUSF were relatively successful for the treatment of moderate acute malnutrition in children. Despite the relatively low ration size provided, the recovery rates observed for both groups were comparable to or higher than those reported in previous studies, a probable effect of nutrition education.

Indexed as

Food, FortifiedGlycine maxWeight GainZea maysAcute DiseaseBody WeightCameroonChild Nutrition DisordersChild, PreschoolFast FoodsFemaleHumansInfantMaleMalnutritionNutritional RequirementsCorn–soya blendModerate acute malnutritionReady-to-use supplementary food

Identifiers

PMID25939394
PMCPMC10270795
OpenAlexW2252814139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.