Evidence map›Paper›PMID 25939069›Full record

ArticleMolecules (Basel, Switzerland)2015

Gd-Complexes of New Arylpiperazinyl Conjugates of DTPA-Bis(amides): Synthesis, Characterization and Magnetic Relaxation Properties.

Abdullah O Ba-Salem, Nisar Ullah, M Nasiruzzaman Shaikh, Mohamed Faiz, Zaheer Ul-Haq

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdullah O Ba-SalemChemistry Department, King Fahd University of Petroleum and Minerals, Dhahran-31261, Saudi Arabia. abdullahbasalem@gmail.com.
Nisar UllahChemistry Department, King Fahd University of Petroleum and Minerals, Dhahran-31261, Saudi Arabia. nullah@kfupm.edu.sa.
M Nasiruzzaman ShaikhCenter of Research Excellence in Nanotechnology, King Fahd University of Petroleum and Minerals, Dhahran-31261, Saudi Arabia. mnshaikh@kfupm.edu.sa.
Mohamed FaizPhysics Department, King Fahd University of Petroleum and Minerals, Dhahran-31261, Saudi Arabia. mmfaiz@kfupm.edu.sa.
Zaheer Ul-HaqDr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. zaheer_qasmi@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new DTPA-bis(amide) based ligands conjugated with the arylpiperazinyl moiety were synthesized and subsequently transformed into their corresponding Gd(III) complexes 1 and 2 of the type [Gd(L)H2O]·nH2O. The relaxivity (R1) of these complexes was measured, which turned out to be comparable with that of Omniscan®, a commercially available MRI contrast agent. The cytotoxicity studies of these complexes indicated that they are non-toxic, which reveals their potential and physiological suitability as MRI contrast agents. All the synthesized ligands and complexes were characterized with the aid of analytical and spectroscopic methods, including elemental analysis, 1H-NMR, FT-IR, XPS and fast atom bombardment (FAB) mass spectrometry.

Indexed as

3T3 CellsAmidesAnimalsCell LineContrast MediaGadoliniumGadolinium DTPALigandsMagnetic Resonance ImagingMicePentetic AcidSpectroscopy, Fourier Transform InfraredWaterAmidesContrast MediagadodiamideGadoliniumGadolinium DTPALigandsPentetic AcidWater

Identifiers

PMID25939069
PMCPMC6272509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.