ArticleJournal of abnormal psychology2015
Do sleep disturbances and psychotic-like experiences in adolescence share genetic and environmental influences?
Article in Journal of abnormal psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sleep and schizophrenia: From epiphenomenon to treatable causal target.Schizophrenia research · 2020Pooled it
- The role of sleep dysfunction in the occurrence of delusions and hallucinations: A systematic review.Clinical psychology review · 2015Pooled it
- Trial
- The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis.The lancet. Psychiatry · 2017Trial
- Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot trial.The lancet. Psychiatry · 2015Trial
- Mental health symptoms in Chinese children with sleep disorders and association with parental emotions.Scientific reports · 2025Article
- Sleep and circadian difficulties in schizophrenia: presentations, understanding, and treatment.Psychological medicine · 2025Review
- Bidirectional associations between short sleep duration, insomnia symptoms, and psychotic-like experiences in adolescents.European child & adolescent psychiatry · 2025Article
- Impaired Sleep Mediates the Relationship Between Interpersonal Trauma and Subtypes of Delusional Ideation.Schizophrenia bulletin · 2024Article
- Sub-types of insomnia in adolescents: Insights from a quantitative/molecular twin study.JCPP advances · 2023Article
- Alexithymia is associated with insomnia in Chinese patients with schizophrenia.Frontiers in psychiatry · 2023Article
- Correlates of psychotic like experiences (PLEs) during Pandemic: An online study investigating a possible link between the SARS-CoV-2 infection and PLEs among adolescents.Schizophrenia research · 2022Article
- Paranoia in patients attending child and adolescent mental health services.The Australian and New Zealand journal of psychiatry · 2021Article
- Psychotic-Like Experiences Associated with Sleep Disturbance and Brain Volumes in Youth: Findings from the Adolescent Brain Cognitive Development Study.JCPP advances · 2021Article
- Actigraphic sleep and cortisol in middle childhood: A multivariate behavioral genetics model.Comprehensive psychoneuroendocrinology · 2021Article
- Genetic overlap and causal associations between smoking behaviours and mental health.Scientific reports · 2021Article
- Polygenic risk scores for major psychiatric and neurodevelopmental disorders contribute to sleep disturbance in childhood: Adolescent Brain Cognitive Development (ABCD) Study.Translational psychiatry · 2021Article
- Sleep Interventions in the Treatment of Schizophrenia and Bipolar Disorder.Noro psikiyatri arsivi · 2021Review
- A Twin Study on the Association Between Psychotic Experiences and Tobacco Use During Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2019Article
- Schizophrenia liability shares common molecular genetic risk factors with sleep duration and nightmares in childhood.Wellcome open research · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Sleep disturbances regularly co-occur with clinical psychotic disorders and dimensions of psychotic-like experiences (PLEs). One possible explanation for this, which has yet to be tested, is that similar genetic or environmental influences underlie sleep disturbances and vulnerability to PLEs. We conducted a twin study to test this possibility in relation to sleep disturbances and six specific PLEs in adolescence in the general population. Approximately 5,000 16-year-old twin pairs completed the Pittsburgh Sleep Quality Index and Insomnia Severity Index. PLEs were assessed using the Specific PLEs Questionnaire, comprising five self-report subscales (Paranoia, Hallucinations, Cognitive Disorganization, Grandiosity, and Anhedonia) and one parent-report subscale (Negative Symptoms). The associations between these measures were tested using structural equation twin model fitting. Paranoia, Hallucinations, and Cognitive Disorganization displayed moderate and significant correlations with both sleep measures (0.32-.42), while Negative Symptoms, Anhedonia, and Grandiosity showed lower correlations (0.01-0.17). Genetic and environmental influences significantly overlapped across PLEs (Paranoia, Hallucinations, Cognitive Disorganization) and both types of sleep disturbance (mean genetic and nonshared environmental correlations = 0.54 and 0.24, respectively). These estimates reduced, yet remained significant, after controlling for negative affect. The association between PLEs with sleep disturbances in adolescence is partly due to genetic and environmental influences that are common to them both. These findings indicate that the known neurobiology of sleep disturbance may provide clues regarding the causes of PLEs in adolescence.
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