Evidence map›Paper›PMID 25938534›Full record

ArticleThe New England journal of medicine2015

Long-term effects of retinal gene therapy in childhood blindness.

Alan F Wright

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.Molecular therapy : the journal of the American Society of Gene Therapy · 2017
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Alan F WrightFrom the MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh.

Funding

Medical Research Council MC_PC_U127584475Medical Research Council MC_U127584475
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic TherapyAnimalscis-trans-IsomerasesDNA, ComplementaryHumansLeber Congenital AmaurosisPhotoreceptor Cells, VertebrateRetinoid Isomerohydrolasecis-trans-IsomerasesDNA, ComplementaryRetinoid Isomerohydrolase

Identifiers

PMID25938534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.