Evidence map›Paper›PMID 25938297›Full record

ArticleJournal of visualized experiments : JoVE2015

Diffusion imaging in the rat cervical spinal cord.

Elizabeth Zakszewski, Brian Schmit, Shekar Kurpad, Matthew D Budde

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. LongitudinalJournal of neurotrauma · 2019
    Article
  7. Article
  8. Article
  9. Interrogating Metabolism in Brain Cancer.Magnetic resonance imaging clinics of North America · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth ZakszewskiDepartment of Neurosurgery, Medical College of Wisconsin; ezakszewski@mcw.edu.
Brian SchmitDepartment of Biomedical Engineering, Marquette University.
Shekar KurpadDepartment of Neurosurgery, Medical College of Wisconsin.
Matthew D BuddeDepartment of Neurosurgery, Medical College of Wisconsin.

Funding

Diffusion Tensor Imaging of the Injured Spinal CordI01RX001497 · VA · CLEMENT J. ZABLOCKI VA MEDICAL CENTER · PI KURPAD, SHEKAR N. · 2014 to 2018
–
RRD VA I01 RX001497
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) is the state of the art approach for assessing the status of the spinal cord noninvasively, and can be used as a diagnostic and prognostic tool in cases of disease or injury. Diffusion weighted imaging (DWI), is sensitive to the thermal motion of water molecules and allows for inferences of tissue microstructure. This report describes a protocol to acquire and analyze DWI of the rat cervical spinal cord on a small-bore animal system. It demonstrates an imaging setup for the live anesthetized animal and recommends a DWI acquisition protocol for high-quality imaging, which includes stabilization of the cord and control of respiratory motion. Measurements with diffusion weighting along different directions and magnitudes (b-values) are used. Finally, several mathematical models of the resulting signal are used to derive maps of the diffusion processes within the spinal cord tissue that provide insight into the normal cord and can be used to monitor injury or disease processes noninvasively.

Indexed as

AnimalsBody WeightCervical CordDiffusion Magnetic Resonance ImagingRats

Identifiers

PMID25938297
PMCPMC4541495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.