Evidence map›Paper›PMID 25938124›Full record

ArticleISRN Addiction2014

An Evaluation of Substance Abuse Treatment and HIV Education on Safe Sex Practices in Cocaine Dependent Individuals.

Theresa M Winhusen, Eugene C Somoza, Daniel F Lewis, Frankie Kropp, Jeff Theobald, Ahmed Elkashef

4 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in ISRN Addiction, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00015106 phase2completednot on this map

CREST-I: Resperine, Gabapentin, or Lamotrigine vs. Placebo

TypeinterventionalSponsorNational Institute on Drug Abuse (NIDA)Ran1997 to 1999Enrolled0ConditionsCocaine-Related DisordersArmsLamotrigine
NCT00015132 phase2completednot on this map

CREST-II: Tiagabine, Sertraline, or Donepezil vs. Unmatched Placebo

TypeinterventionalSponsorNational Institute on Drug Abuse (NIDA)Ran1999 to 2000Enrolled0ConditionsCocaine-Related DisordersArmsSertraline
NCT00033033 phase2completednot on this map

Phase 2, Double-Blind, Placebo-Controlled Trial of Reserpine for the Treatment of Cocaine Dependence

TypeinterventionalSponsorNational Institute on Drug Abuse (NIDA)Ran2001 to 2003Enrolled140ConditionsCocaine-Related Disorders, Substance-Related DisordersArmsReserpine
NCT00086255 phase2completednot on this map

Tiagabine for the Treatment of Cocaine Dependence

TypeinterventionalSponsorNational Institute on Drug Abuse (NIDA)Ran2002 to 2004Enrolled140ConditionsCocaine-Related DisordersArmsTiagabine
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Theresa M WinhusenAddiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA.
Eugene C SomozaAddiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA ; Veterans Affairs Medical Center (VISN 10), 3200 Vine Street, Cincinnati, OH 45220, USA.
Daniel F LewisAddiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA.
Frankie KroppAddiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA.
Jeff TheobaldAddiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH 45229, USA.
Ahmed ElkashefNational Rehabilitation Center, P.O. Box 55001, Abu Dhabi, United Arab Emirates.
University of Cincinnati Medical Center · USAbu Dhabi National Oil (United Arab Emirates) · AEVA Northeast Ohio Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. There is a strong association between crack/cocaine use and increased sexual risk behavior, but little research on the efficacy of HIV education for decreasing such behavior in crack/cocaine-addicted individuals in substance abuse treatment. Method. Datasets from two cocaine dependence trials including either one or three HIV education sessions, respectively, were analyzed for changes over time in the proportion of participants practicing safe sex. A pooled dataset from two earlier trials not offering HIV education was also analyzed. Results. We included 83 participants from the 1-session trial and 65 participants from the 3-session trial. Both sets of participants evidenced a significant increase in the proportion of participants having safe sex with casual partners. Participants in the 3-session HIV education study also evidenced a significant increase in the proportion of participants having safe sex with regular partners. In the trials without HIV education, no change in safe sex practices was found, and change in condom use was observed only among female participants. Conclusions. These findings are consistent with recommendations that HIV education/counseling should be provided to individuals in substance abuse treatment. A randomized controlled trial to confirm these results may be warranted. This trial is registered with NCT00033033, NCT00086255, NCT00015106, and NCT00015132.

Identifiers

PMID25938124
PMCPMC4392976
OpenAlexW2059953026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.