Evidence map›Paper›PMID 25937787›Full record

ArticleSupramolecular chemistry2015

Synthesis of a Disulfonated Derivative of Cucurbit[7]uril and Investigations of its Ability to Solubilize Insoluble Drugs.

Elizabeth L Robinson, Peter Y Zavalij, Lyle Isaacs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supramolecular chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth L RobinsonDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Peter Y ZavalijDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Lyle IsaacsDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.

Funding

Acyclic Cucurbit n uril Molecular Containers for Drug Solubilization and DeliveryR01CA168365 · NCI · UNIV OF MARYLAND, COLLEGE PARK · PI BRIKEN, VOLKER, ISAACS, LYLE D · 2013 to 2017
$1.9M
NCI NIH HHS R01 CA168365
6 · The paper itself

Abstract

Cucurbit[7]uril (CB[7]) is currently being investigated as a solubilizing agent for insoluble drugs. We recently found that acyclic CB[n]-type receptors that bear sulfonate solubilizing groups are well suited for this application. Herein, we report cucurbit[7]uril derivative (

Identifiers

PMID25937787
PMCPMC4412466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.