Evidence map›Paper›PMID 25937786›Full record

ArticleSupramolecular chemistry

Cyclodextrin-promoted energy transfer for broadly applicable small-molecule detection.

Nicole Serio, Chitapom Chanthalyma, Lindsey Prignano, Mindy Levine

Abstract read
In one paragraph

Article in Supramolecular chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole SerioDepartment of Chemistry, University of Rhode Island, 51 Lower College Road, Kingston, RI 02881, USA.
Chitapom ChanthalymaDepartment of Chemistry, University of Rhode Island, 51 Lower College Road, Kingston, RI 02881, USA.
Lindsey PrignanoDepartment of Chemistry, University of Rhode Island, 51 Lower College Road, Kingston, RI 02881, USA.
Mindy LevineDepartment of Chemistry, University of Rhode Island, 51 Lower College Road, Kingston, RI 02881, USA.

Funding

(PQA4) Detecting carcinogens in complex environments via energy transferR21CA185435 · NCI · UNIVERSITY OF RHODE ISLAND · PI LEVINE, MINDY · 2014 to 2015
$341k
NCI NIH HHS R21 CA185435
6 · The paper itself

Abstract

Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

Indexed as

cyclodextrinenergy transferfluorescence spectroscopy

Identifiers

PMID25937786
PMCPMC4415731

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.