Evidence map›Paper›PMID 25937524›Full record

ReviewEuropean journal of radiology2015

Cancer immunotherapy and immune-related response assessment: The role of radiologists in the new arena of cancer treatment.

Mizuki Nishino, Sree H Tirumani, Nikhil H Ramaiya, F Stephen Hodi

Abstract readReview
In one paragraph

Review in European journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 116 citations in OpenAlex.

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  6. PD-1 Inhibitor-Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course.Clinical cancer research : an official journal of the American Association for Cancer Research · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mizuki NishinoDepartment of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address: Mizuki_Nishino@DFCI.HARVARD.EDU.
Sree H TirumaniDepartment of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
Nikhil H RamaiyaDepartment of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
F Stephen HodiDepartment of Medical Oncology and Department of Medicine, Dana-Farber Cancer Institute and Brigham and Women's Hospital, 450 Brookline Ave., Boston, MA 02215, USA.
Brigham and Women's Hospital · US

Funding

CT Volume Measurement of Lung Cancer treated with Erlotinib: Genomic CorrelationK23CA157631 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI NISHINO, MIZUKI · 2011 to 2015
$902k
NCI NIH HHS 1K23CA157631NCI NIH HHS K23 CA157631
6 · The paper itself

Abstract

The recent advances in the clinical application of anti-cancer immunotherapeutic agents have opened a new arena for the treatment of advanced cancers. Cancer immunotherapy is associated with a variety of important radiographic features in the assessments of tumor response and immune-related adverse events, which calls for radiologists' awareness and in-depth knowledge on the topic. This article will provide the state-of-the art review and perspectives of cancer immunotherapy, including its molecular mechanisms, the strategies for immune-related response assessment on imaging and their pitfalls, and the emerging knowledge of radiologic manifestations of immune-related adverse events. The cutting edge clinical and radiologic investigations are presented to provide future directions.

Indexed as

ImmunotherapyAntibodies, MonoclonalAntineoplastic AgentsCancer VaccinesCombined Modality TherapyHumansNeoplasmsT-Lymphocytes, RegulatoryAntibodies, MonoclonalAntineoplastic AgentsCancer VaccinesCancerDrug toxicityImmunotherapyOncologic imagingTumor response assessment

Identifiers

PMID25937524
PMCPMC4450141
OpenAlexW2137264248

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.