Evidence map›Paper›PMID 25936911›Full record

ArticleAllergy, asthma & immunology research2015

Effect of Traffic-Related Air Pollution on Allergic Disease: Results of the Children's Health and Environmental Research.

Dal Young Jung, Jong Han Leem, Hwan Cheol Kim, Jeong Hee Kim, Seung Sik Hwang, Ji Young Lee, Byoung Ju Kim, Yun Chul Hong, Soo Jong Hong, Ho Jang Kwon

Abstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Risk Factors of Child Lead Poisoning in China: A Meta-Analysis.International journal of environmental research and public health · 2016
    Pooled it
  2. The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases.World journal of otorhinolaryngology - head and neck surgery · 2026
    Review
  3. Unmasking the Impact of Air Pollution on Allergic Rhinitis.Clinical reviews in allergy & immunology · 2026
    Review
  4. Article
  5. Climate Change and the Future of Allergies and Asthma.Current allergy and asthma reports · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Loss of E-cadherin due to road dust PMEnvironmental science and pollution research international · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Proximity to Major Roads and Risks of Childhood Recurrent Wheeze and Asthma in a Severe Bronchiolitis Cohort.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dal Young JungDepartment of Social and Preventive Medicine, Inha University School of Medicine, Incheon, Korea.
Jong Han LeemDepartment of Social and Preventive Medicine, Inha University School of Medicine, Incheon, Korea.; Department of Occupational and Environmental Medicine, Inha University hospital, Incheon, Korea. ekeeper@inha.ac.kr.
Hwan Cheol KimDepartment of Social and Preventive Medicine, Inha University School of Medicine, Incheon, Korea.; Department of Occupational and Environmental Medicine, Inha University hospital, Incheon, Korea.
Jeong Hee KimDepartment of Pediatrics, Inha University School of Medicine, Incheon, Korea.
Seung Sik HwangDepartment of Social and Preventive Medicine, Inha University School of Medicine, Incheon, Korea.
Ji Young LeeDepartment of Social and Preventive Medicine, Inha University School of Medicine, Incheon, Korea.
Byoung Ju KimDepartment of Pediatrics, Inje University Haeundae Paik Hospital, Busan, Korea.
Yun Chul HongDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Soo Jong HongDepartment of Pediatrics, Childhood Asthma Atopy Center, Research Center for Standardization of Allergic Diseases, University of Ulsan College of Medicine, Seoul, Korea.
Ho Jang KwonDepartment of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the relationship of living near to main roads to allergic diseases, airway hyperresponsiveness (AHR), allergic sensitization, and lung function in Korean children.

methodsA total of 5,443 children aged 6-14 years from 33 elementary schools in 10 cities during 2005-2006 were included in a baseline survey of the Children's Health and Environmental Research. We assessed association of traffic-related air pollution (TAP) exposure with the distance to the nearest main road, total road length of main roads and the proportion of the main road area within the 200-m home area.

resultsPositive exposure-response relationships were found between the length of the main road within the 200-m home area and lifetime wheeze (adjusted prevalence ratio [PR] for comparison of the longest to the shortest length categories=1.24; 95% CIs, 1.04-1.47; P for trend=0.022) and diagnosed asthma (PR=1.42; 95% CIs, 1.08-1.86; P for trend=0.011). Living less than 75 m from the main road was significantly associated with lifetime allergic rhinitis (AR), past-year AR symptoms, diagnosed AR, and treated AR. The distance to the main road (P for trend=0.001), the length of the main road (P for trend=0.041), and the proportion of the main road area (P for trend=0.006) had an exposure-response relationship with allergic sensitization. A strong inverse association was observed between residential proximity to the main load and lung function, especially FEV1, FEV1/FVC, and FEF₂₅₋₇₅. The length of the main road and the proportion of the main road area were associated with reduced FEV1 in schoolchildren.

conclusionsThe results of this study suggest that exposure to traffic-related air pollution may be associated with increased risk of asthma, AR, and allergic sensitization, and with reduced lung function in schoolchildren.

Indexed as

Air pollutionallergic rhinitisasthmabronchial hyperreactivitychildrespiratory function tests

Identifiers

PMID25936911
PMCPMC4446634

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.