Evidence map›Paper›PMID 25936425›Full record

ArticlePsychological medicine2015

Diagnostic change 10 years after a first episode of psychosis.

M Heslin, B Lomas, J M Lappin, K Donoghue, U Reininghaus, A Onyejiaka, T Croudace, P B Jones, R M Murray, P Fearon and 3 more

Abstract read
In one paragraph

Article in Psychological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Guidelines for the Pharmacotherapy of Schizophrenia in Adults.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2017
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  18. Mortality in psychotic depression: 18-year follow-up study.The British journal of psychiatry : the journal of mental science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

M HeslinCentre for Economics of Mental and Physical Health,King's College London,London,UK.
B LomasDivision of Psychiatry,University of Nottingham,Nottingham,UK.
J M LappinDepartment of Psychiatry,University of New South Wales,Sydney,Australia.
K DonoghueAddictions Department,King's College London,London,UK.
U ReininghausCentre for Epidemiology and Public Health,King's College London,London,UK.
A OnyejiakaDepartment of Psychology,King's College London,London,UK.
T CroudaceSchool of Nursing and Midwifery,College of Medicine, Dentistry and Nursing,University of Dundee,Dundee,UK.
P B JonesDepartment of Psychiatry,University of Cambridge,Cambridge,UK.
R M MurrayPsychosis Studies Department,King's College London,London,UK.
P FearonDepartment of Psychiatry,Trinity College,Dublin,Republic of Ireland.
P DazzanPsychosis Studies Department,King's College London,London,UK.
C MorganCentre for Epidemiology and Public Health,King's College London,London,UK.
G A DoodyDivision of Psychiatry,University of Nottingham,Nottingham,UK.

Funding

Medical Research Council G0500817Medical Research Council G0600972Medical Research Council G106/1148Medical Research Council MC_PC_13042Medical Research Council MR/K006665/1
6 · The paper itself

Abstract

backgroundA lack of an aetiologically based nosology classification has contributed to instability in psychiatric diagnoses over time. This study aimed to examine the diagnostic stability of psychosis diagnoses using data from an incidence sample of psychosis cases, followed up after 10 years and to examine those baseline variables which were associated with diagnostic change.

methodData were examined from the ÆSOP and ÆSOP-10 studies, an incidence and follow-up study, respectively, of a population-based cohort of first-episode psychosis cases from two sites. Diagnosis was assigned using ICD-10 and DSM-IV-TR. Diagnostic change was examined using prospective and retrospective consistency. Baseline variables associated with change were examined using logistic regression and likelihood ratio tests.

resultsSlightly more (59.6%) cases had the same baseline and lifetime ICD-10 diagnosis compared with DSM-IV-TR (55.3%), but prospective and retrospective consistency was similar. Schizophrenia, psychotic bipolar disorder and drug-induced psychosis were more prospectively consistent than other diagnoses. A substantial number of cases with other diagnoses at baseline (ICD-10, n = 61; DSM-IV-TR, n = 76) were classified as having schizophrenia at 10 years. Many variables were associated with change to schizophrenia but few with overall change in diagnosis.

conclusionsDiagnoses other than schizophrenia should to be regarded as potentially provisional.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersAdultBipolar DisorderCohort StudiesDiagnosis, DifferentialFemaleHumansInternational Classification of DiseasesLogistic ModelsMalePsychotic DisordersSchizophreniaYoung AdultDiagnosisfirst-episode psychosispsychoses

Identifiers

PMID25936425
PMCPMC4595854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.