Evidence map›Paper›PMID 25936226›Full record

ReviewTrends in parasitology2015

Tick microbiome: the force within.

Sukanya Narasimhan, Erol Fikrig

Open access · greenAbstract readReview
In one paragraph

Review in Trends in parasitology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 2 pooled it
18.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 2 syntheses or guidelines pooled it, 362 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  7. Article
  8. Review
  9. bioRxiv : the preprint server for biology · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Current research in parasitology & vector-borne diseases · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Advances in the use of entomopathogenic fungi to control ixodid ticks.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026
    Review
  20. Article

128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sukanya NarasimhanSection of Infectious Diseases, Department of Internal Medicine, Yale University, New Haven, CT, USA. Electronic address: sukanya.narasimhan@yale.edu.
Erol FikrigSection of Infectious Diseases, Department of Internal Medicine, Yale University, New Haven, CT, USA; The Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: erol.fikrig@yale.edu.
Yale University · US

Funding

BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARISR01AI032947 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL · 1998 to 2012
$5.1M
Tick Midgut Proteins Critical for Borrelia TransmissionR21AI076705 · NIAID · YALE UNIVERSITY · PI NARASIMHAN, SUKANYA · 2009 to 2010
$455k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI032947NIAID NIH HHS R21 AI076705
6 · The paper itself

Abstract

Ticks are obligate blood-feeders and serve as vectors of human and livestock pathogens worldwide. Defining the tick microbiome and deciphering the interactions between the tick and its symbiotic bacteria in the context of tick development and pathogen transmission will likely reveal new insights and spawn new paradigms to control tick-borne diseases. Descriptive observations on the tick microbiome that began almost a century ago serve as forerunners to the gathering momentum to define the tick microbiome in greater detail. This review will focus on the current efforts to address the microbiomes of diverse ticks, and the evolving understanding of tick microbiomes. There is hope that these efforts will bring a holistic understanding of pathogen transmission by ticks.

Indexed as

Bacterial Physiological PhenomenaAnimalsMicrobiotaTick-Borne DiseasesTickstick endosymbiontstick microbiome

Identifiers

PMID25936226
PMCPMC4492851
OpenAlexW2081212060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.