Evidence map›Paper›PMID 25935896›Full record

ArticleJournal of public health (Oxford, England)2016

The relationship between changes in sitting time and mortality in post-menopausal US women.

J Lee, J L Kuk, C I Ardern

Abstract read
In one paragraph

Article in Journal of public health (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Patterns of sitting and mortality in the Nord-Trøndelag health study (HUNT).The international journal of behavioral nutrition and physical activity · 2017
    Article
  8. Impact of changes in television viewing time and physical activity on longevity: a prospective cohort study.The international journal of behavioral nutrition and physical activity · 2015
    Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J LeeSchool of Kinesiology and Health Science, York University, Toronto, Ontario, Canada M3J1P3.
J L KukSchool of Kinesiology and Health Science, York University, Toronto, Ontario, Canada M3J1P3.
C I ArdernSchool of Kinesiology and Health Science, York University, Toronto, Ontario, Canada M3J1P3.

Funding

CIHR 131594
6 · The paper itself

Abstract

backgroundProlonged sitting is linked to various deleterious health outcomes. The alterability of the sitting time (ST)-health relationship is not fully established however and warrants study within populations susceptible to high ST.

methodsWe assessed the mortality rates of post-menopausal women from the Women's Health Initiative (WHI) observational study, a 15-year prospective study of post-menopausal women aged 50-79 years, according to their change in ST between baseline and year six. A total of 77 801 participants had information at both times on which to be cross-classified into the following: (i) high ST at baseline and follow-up; (ii) low ST at baseline and follow-up; (iii) increased ST and (iv) decreased ST. Cox regression was used to assess the relationship between all-cause, CVD and cancer mortality with change in ST.

resultsAt the end of follow-up, there were 1855 deaths. Compared with high ST maintainers, low ST maintainers had a 51 and 48% lower risk of all-cause and cancer mortality, respectively. Reducing sitting also resulted in a protective rate of 29% for all-cause and 27% for cancer mortality.

conclusionsThese results highlight not only the benefit of maintaining minimal ST, but also the utility of decreasing ST in older women, if current levels are high.

Indexed as

Sedentary BehaviorAgedAged, 80 and overAlcohol DrinkingCause of DeathChronic DiseaseFemaleHumansMiddle AgedMortalityNeoplasmsPostmenopausePostureProportional Hazards ModelsProspective StudiesRisk Factorschronic diseasecohort studylife expectancylifestylesedentary

Identifiers

PMID25935896
PMCPMC4894483

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.