Trial reportAIDS and behavior2015
Assessment of contamination and misclassification biases in a randomized controlled trial of a social network peer education intervention to reduce HIV risk behaviors among drug users and risk partners in Philadelphia, PA and Chiang Mai, Thailand.
Trial report in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- Overall, Direct, Spillover, and Composite Effects of Components of a Peer-Driven Intervention Package on Injection Risk Behavior Among People Who Inject Drugs in the HPTN 037 Study.AIDS and behavior · 2024Trial
- A Web-Based Sexual Violence, Alcohol Misuse, and Bystander Intervention Program for College Women (RealConsent): Randomized Controlled Trial.Journal of medical Internet research · 2023Trial
- Evaluating network-level predictors of behavior change among injection networks enrolled in the HPTN 037 randomized controlled trial.Drug and alcohol dependence · 2017Trial
- Sensitivity analysis for contamination in egocentric-network randomized trials with interference.Biostatistics (Oxford, England) · 2026Article
- Estimation and inference for causal spillover effects in egocentric-network randomized trials in the presence of network membership misclassification.Biostatistics (Oxford, England) · 2025Article
- Contamination bias in the estimation of child maltreatment causal effects on adolescent internalizing and externalizing behavior problems.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Aniqsaaq (To Breathe): Study protocol to develop and evaluate an Alaska Native family-based financial incentive intervention for smoking cessation.Contemporary clinical trials communications · 2023Article
- Methods for Assessing Spillover in Network-Based Studies of HIV/AIDS Prevention among People Who Use Drugs.Pathogens (Basel, Switzerland) · 2023Article
- Evaluating the Mediating Role of Recall of Intervention Knowledge in the Relationship Between a Peer-Driven Intervention and HIV Risk Behaviors Among People Who Inject Drugs.AIDS and behavior · 2023Article
- A crowdsourced intervention to promote hepatitis B and C testing among men who have sex with men in China: A nationwide online randomized controlled trial.EClinicalMedicine · 2019Article
- HIV prevention intervention for substance users: a review of the literature.Substance abuse treatment, prevention, and policy · 2019Review
- School-based interventions for reducing disciplinary school exclusion: a systematic review.Campbell systematic reviews · 2018Article
- Using Digital Technologies in Clinical HIV Research: Real-World Applications and Considerations for Future Work.Journal of medical Internet research · 2017Article
- Social Network Strategies to Address HIV Prevention and Treatment Continuum of Care Among At-risk and HIV-infected Substance Users: A Systematic Scoping Review.AIDS and behavior · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Controlled trials of HIV prevention and care interventions are susceptible to contamination. In a randomized controlled trial of a social network peer education intervention among people who inject drugs and their risk partners in Philadelphia, PA and Chiang Mai, Thailand, we tested a contamination measure based on recall of intervention terms. We assessed the recall of test, negative and positive control terms among intervention and control arm participants and compared the relative odds of recall of test versus negative control terms between study arms. The contamination measures showed good discriminant ability among participants in Chiang Mai. In Philadelphia there was no evidence of contamination and little evidence of diffusion. In Chiang Mai there was strong evidence of diffusion and contamination. Network structure and peer education in Chiang Mai likely led to contamination. Recall of intervention materials can be a useful method to detect contamination in experimental interventions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.