Evidence map›Paper›PMID 25935145›Full record

Trial reportEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017

Continuous wound infusion of ropivacaine for the control of pain after thoracolumbar spinal surgery: a randomized clinical trial.

Bo Xu, Li Ren, Weifeng Tu, Zenghui Wu, Fuzhi Ai, Dongxu Zhou, Biyun Chen, Xingan Zhang

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
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  5. Trial
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  8. Review
  9. Pain control following posterior spine fusion: patient-controlled continuous epidural catheter infusion method yields better post-operative analgesia control compared to intravenous patient controlled analgesia method. A retrospective case series.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bo XuDepartment of Anesthesiology, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China. xubo333@hotmaill.com.
Li RenDepartment of Anesthesiology, Zhuhai People's Hospital, Zhuhai, 519000, China.
Weifeng TuDepartment of Anesthesiology, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China. gzzyyubox@gmail.com.
Zenghui WuDepartment of Orthopedics, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China.
Fuzhi AiDepartment of Orthopedics, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China.
Dongxu ZhouDepartment of Anesthesiology, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China.
Biyun ChenDepartment of Anesthesiology, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China.
Xingan ZhangDepartment of Anesthesiology, General Hospital of Guangzhou Military Command, Guangzhou, 510010, China.
General Hospital of Guangzhou Military Command · CNZhuhai People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA prospective randomized clinical trial was carried out to observe the analgesic efficacy of ropivacaine for postoperative pain following thoracolumbar spinal surgery.

methodsSeventy-one patients with elective posterior thoracolumbar spinal surgery were randomly divided into two groups. Local group received 0.33 % ropivacaine by pump through the wound, and intravenous group received flurbiprofen axetil, pentazocine and palonosetron via intravenous pump. We evaluated the level of pain, the incidence of adverse reactions at 2, 4, 6, 12, 24, 36 and 48 h after operation, and the occurrence of chronic pain 3 months later.

resultsThere were no significant differences in the pain level between the two groups. However, the incidence of nausea, vomiting and chronic pain was significantly lower in the local group.

conclusionsOur results showed that local infusion of ropivacaine achieved similar analgesic effects to intravenous delivery of analgesic drugs, but significantly reduced incidence of nausea, vomiting and chronic pain.

Indexed as

AmidesAnesthetics, LocalPostoperative PainAnesthesia, LocalHumansLumbar VertebraeOrthopedic ProceduresPain MeasurementRopivacaineThoracic VertebraeAmidesAnesthetics, LocalRopivacaineChronic painLocal analgesiaPostoperative painRopivacaineThoracolumbar spinal surgery

Identifiers

PMID25935145
OpenAlexW2052598279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.