Evidence map›Paper›PMID 25934458›Full record

Trial reportJournal of substance abuse treatment2015

The Impact of Exercise On Depression and Anxiety Symptoms Among Abstinent Methamphetamine-Dependent Individuals in A Residential Treatment Setting.

Richard A Rawson, Joy Chudzynski, Rachel Gonzales, Larissa Mooney, Daniel Dickerson, Alfonso Ang, Brett Dolezal, Christopher B Cooper

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of substance abuse treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 13 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 13 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Exercise for depression.The Cochrane database of systematic reviews · 2026
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  13. Methamphetamine-Related Disorders.Deutsches Arzteblatt international · 2017
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  16. Effect of Exercise Training on Striatal Dopamine D2/D3 Receptors in Methamphetamine Users during Behavioral Treatment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Richard A RawsonIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. Electronic address: rrawson@mednet.ucla.edu.
Joy ChudzynskiIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Rachel GonzalesIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Larissa MooneyIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Daniel DickersonIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Alfonso AngIntegrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Brett DolezalExercise Physiology Research Laboratory, Division of Pulmonary Medicine, David Geffen School of Medicine, 10833 Le Conte 37-131 CHS, University of California, Los Angeles, CA, USA.
Christopher B CooperExercise Physiology Research Laboratory, Division of Pulmonary Medicine, David Geffen School of Medicine, 10833 Le Conte 37-131 CHS, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Aerobic Exercise to Improve Outcomes of Treatment for Methamphetamine DependenceR01DA027633 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAWSON, RICHARD A · 2009 to 2014
$2.7M
NIDA NIH HHS R01 DA027633
6 · The paper itself

Abstract

backgroundThis paper reports data from a study designed to determine the impact of an 8-week exercise program on depression and anxiety symptoms among newly abstinent methamphetamine (MA)-dependent individuals in residential treatment.

methodsOne hundred thirty-five MA-dependent individuals, newly enrolled in residential treatment, were randomly assigned to receive either a 3-times-per-week, 60-minute structured exercise program for 8 weeks (24 sessions) or an equivalent number of health education sessions. Using mixed-modeling repeated-measures regression, we examined changes in weekly total depression and anxiety scores as measured by the Beck Depression Inventory and Beck Anxiety Inventory over the 8-week study period.

resultsMean age of participants was 31.7 (SD = 6.9); 70.4% were male and 48% Latino. Analyses indicate a significant effect of exercise on reducing depression (β = -0.63, P = 0.001) and anxiety (β = -0.95, P=0.001) symptoms (total scores) over the 8-week period compared to a health education control group. A significant dose interaction effect between session attendance and exercise was found as well on reducing depression (β = -0.61, P < 0.001) and anxiety symptoms (β = -0.22, P=0.009) over time compared to the control group.

conclusionsResults support the role of a structured exercise program as an effective intervention for improving symptoms of depression and anxiety associated with MA abstinence.

Indexed as

Central Nervous System StimulantsMethamphetamineAdolescentAdultAmphetamine-Related DisordersAnxietyDepressionExercise TherapyFemaleHumansMaleMiddle AgedResidential TreatmentYoung AdultCentral Nervous System StimulantsMethamphetamineDepression and anxiety symptomsExerciseMethamphetamineTreatment

Identifiers

PMID25934458
PMCPMC4560957
OpenAlexW2144023489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.