ArticleActa biomaterialia2015
Micromechanical poroelastic finite element and shear-lag models of tendon predict large strain dependent Poisson's ratios and fluid expulsion under tensile loading.
Article in Acta biomaterialia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Tendinopathy alters the time course of free achilles tendon morphological recovery following eccentric exercise.Scientific reports · 2026Article
- Contact-induced continuous electricity generation by ion-electron positive feedback coupled transport for self-powered ionic touch panel.Microsystems & nanoengineering · 2026Article
- Novel Insights Into the Intratendinous Pressure Behavior of the Achilles Tendon in Athletes.Sports health · 2025Observational
- Article
- Exploring the role of intratendinous pressure in the pathogenesis of tendon pathology: a narrative review and conceptual framework.British journal of sports medicine · 2023Review
- An indentation-based framework for probing the glycosaminoglycan-mediated interactions of collagen fibrils.Journal of the mechanical behavior of biomedical materials · 2023Article
- Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation.Journal of visualized experiments : JoVE · 2023Article
- Fatigue-free artificial ionic skin toughened by self-healable elastic nanomesh.Nature communications · 2022Article
- The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review.Journal of biomechanical engineering · 2022Review
- Multi-Scale Loading and Damage Mechanisms of Plantaris and Rat Tail Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Modelling human pathology of traumatic brain injury in animal models.Journal of internal medicine · 2019Review
- Biomaterials to Mimic and Heal Connective Tissues.Advanced materials (Deerfield Beach, Fla.) · 2019Review
- Strong triaxial coupling and anomalous Poisson effect in collagen networks.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice.Journal of biomechanical engineering · 2018Article
- Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Article
- Tendon exhibits complex poroelastic behavior at the nanoscale as revealed by high-frequency AFM-based rheology.Journal of biomechanics · 2017Article
- Multiscale regression modeling in mouse supraspinatus tendons reveals that dynamic processes act as mediators in structure-function relationships.Journal of biomechanics · 2016Article
- Neuromechanics and Pathophysiology of Diffuse Axonal Injury in Concussion.Bridge (Washington, D.C. : 1969) · 2016Article
- Evaluating changes in tendon crimp with fatigue loading as an ex vivo structural assessment of tendon damage.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015Article
- Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon.Journal of tissue engineeringArticle
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5 authors.
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Abstract
As tendons are loaded, they reduce in volume and exude fluid to the surrounding medium. Experimental studies have shown that tendon stretching results in a Poisson's ratio greater than 0.5, with a maximum value at small strains followed by a nonlinear decay. Here we present a computational model that attributes this macroscopic observation to the microscopic mechanism of the load transfer between fibrils under stretch. We develop a finite element model based on the mechanical role of the interfibrillar-linking elements, such as thin fibrils that bridge the aligned fibrils or macromolecules such as glycosaminoglycans (GAGs) in the interfibrillar sliding and verify it with a theoretical shear-lag model. We showed the existence of a previously unappreciated structure-function mechanism whereby the Poisson's ratio in tendon is affected by the strain applied and interfibrillar-linker properties, and together these features predict tendon volume shrinkage under tensile loading. During loading, the interfibrillar-linkers pulled fibrils toward each other and squeezed the matrix, leading to the Poisson's ratio larger than 0.5 and fluid expulsion. In addition, the rotation of the interfibrillar-linkers with respect to the fibrils at large strains caused a reduction in the volume shrinkage and eventual nonlinear decay in Poisson's ratio at large strains. Our model also predicts a fluid flow that has a radial pattern toward the surrounding medium, with the larger fluid velocities in proportion to the interfibrillar sliding.
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