Evidence map›Paper›PMID 25933822›Full record

ReviewPhysiology (Bethesda, Md.)2015

Impact of maternal obesity on fetal programming of cardiovascular disease.

Victoria H J Roberts, Antonio E Frias, Kevin L Grove

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effect of maternal diabetes on fetal heart function on echocardiography: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021
    Pooled it
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  8. The Cardiovascular Disease (CVD) Risk Continuum from Prenatal Life to Adulthood: A Literature Review.International journal of environmental research and public health · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Victoria H J RobertsDivision of Diabetes, Obesity & Metabolism, Oregon National Primate Research Center, Beaverton, Oregon; and robertsv@ohsu.edu.
Antonio E FriasDivision of Diabetes, Obesity & Metabolism, Oregon National Primate Research Center, Beaverton, Oregon; and Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon.
Kevin L GroveDivision of Diabetes, Obesity & Metabolism, Oregon National Primate Research Center, Beaverton, Oregon; and.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
The Impact of Maternal Health and Diet on Development of Fetal Metabolic SystemsR24DK090964 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI AAGAARD, KJERSTI MARIE, FRIEDMAN, JACOB E · 2010 to 2019
$15.8M
Dynamic contrast-enhanced MRI of placental circulationR21HD076265 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI FRIAS, ANTONIO E · 2013 to 2014
$474k
NICHD NIH HHS R21 HD076265NICHD NIH HHS R21-HD-076265NIDDK NIH HHS R24 DK090964NIDDK NIH HHS R24-DK-090964NIH HHS P51 OD011092NIH HHS P51-OD-011092
6 · The paper itself

Abstract

The in utero environment is a key determinant of long-term health outcomes; poor maternal metabolic state and placental insufficiency are strongly associated with these long-term health risks. Human epidemiological studies link maternal obesity and offspring cardiovascular disease in later life, but mechanistic studies in animal models are limited. Here, we review the literature pertaining to maternal consequences of obesity during pregnancy and the subsequent impact on fetal cardiovascular development.

Indexed as

EpidemicsMaternal Nutritional Physiological PhenomenaPrenatal Exposure Delayed EffectsAnimalsBody WeightCardiovascular DiseasesCardiovascular SystemFemaleFetal HeartHumansObesityOrganogenesisPlacentaPregnancyPrognosisRisk Factors

Identifiers

PMID25933822
PMCPMC4422977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.