Evidence map›Paper›PMID 25933679›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016

Interpolated average CT for cardiac PET/CT attenuation correction.

Greta S P Mok, Cobie Y T Ho, Bang-Hung Yang, Tung-Hsin Wu

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Simultaneous reconstruction of attenuation and activity in cardiac PET can remove CT misalignment artifacts.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Greta S P MokBiomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau, SAR, China. gretamok@gmail.com.
Cobie Y T HoBiomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau, SAR, China.
Bang-Hung YangDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan.
Tung-Hsin WuDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreviously, we proposed interpolated averaged CT (IACT) for improved attenuation correction (AC) in thoracic PET/CT. This study aims to evaluate its feasibility and effectiveness on cardiac PET/CT.

methodsWe simulated (18)F-FDG distribution using the XCAT phantom with normal and abnormal cardiac uptake. Average activity and attenuation maps represented static PET and respiration average CT (ACT), respectively, while the attenuation maps of end-inspiration/expiration represented 2 helical CTs (HCT). IACT was obtained by averaging the 2 extreme phases and the interpolated phases generated between them. Later, we recruited 4 patients who were scanned 1 hr post 315-428 MBq (18)F-FDG injection. Simulated and clinical PET sinograms were reconstructed with AC using (1) HCT, (2) IACT, and (3) ACT. Polar plots and the 17-segment plots were analyzed. Two regions-of-interest were drawn on lesion and background area to obtain the intensity ratio (IR).

resultsPolar plots of PETIACT-AC were more similar to PETACT-AC in both simulation and clinical data. Artifacts were observed in various segments in PETHCT-AC. IR differences of HCT as compared to the phantom were up to ~20%.

conclusionsIACT-AC reduced respiratory artifacts and improved PET/CT matching similarly to ACT-AC. It is a promising low-dose alternate of ACT for cardiac PET/CT.

Indexed as

ArtifactsAdultAgedAged, 80 and overAlgorithmsCoronary Artery DiseaseFeasibility StudiesHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalInformation Storage and RetrievalMaleMiddle AgedMyocardial Perfusion ImagingNumerical Analysis, Computer-Assistedattenuation correctioncardiac imagingPET/CTrespiratory artifacts

Identifiers

PMID25933679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.