ArticleDevelopmental cognitive neuroscience2015
Forgetting the best when predicting the worst: Preliminary observations on neural circuit function in adolescent social anxiety.
Article in Developmental cognitive neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- The Transdiagnostic Origins of Anxiety and Depression During the Pediatric Period: Linking NIMH Research Domain Criteria (RDoC) Constructs to Ecological Systems.Development and psychopathology · 2021Pooled it
- Social anxiety and the positive valence system: A scoping review.Journal of mood and anxiety disorders · 2026Review
- Increased and Coupled ERP and fMRI Responses toward Positive Social Evaluative Feedback: An EEG-fMRI Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Functional connectivity of the nucleus accumbens and the amygdala in offspring of parents with bipolar or major depressive disorder.European archives of psychiatry and clinical neuroscience · 2026Article
- Social Evaluation in Emerging Adults: Associations with Interpretation Bias and Perceived Social Support.Child psychiatry and human development · 2025Article
- Dopamine function in adolescent social anxiety: Insights from neuromelanin-sensitive MRI.Journal of mood and anxiety disorders · 2025Article
- The Cerebellum and Striatum in Reward Processing: Caring About Being Right vs. Caring About Reward.bioRxiv : the preprint server for biology · 2025Article
- Targeting the dorsolateral prefrontal cortex to enhance memory control: divergent effects on social and non-social memories.Social cognitive and affective neuroscience · 2025Article
- Influence of core self-evaluation on social anxiety in college students with financial difficulties: mediation of self-acceptance.Frontiers in psychology · 2025Article
- The relationship between perceived social support and social anxiety in Chongqing rural secondary school students: the chain mediating effect of core self-evaluation and shyness.BMC psychology · 2024Article
- Higher Intersubject Variability in Neural Response to Narrative Social Stimuli Among Youth With Higher Social Anxiety.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Article
- Corticostriatal Responses to Social Reward are Linked to Trait Reward Sensitivity and Subclinical Substance Use in Young Adults.bioRxiv : the preprint server for biology · 2024Article
- Social feedback biases emerge during recall but not prediction and shift across the development of social anxiety.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice.Biomedicines · 2023Article
- Neural sensitivity to peer feedback and depression symptoms in adolescents: a 2-year multiwave longitudinal study.Journal of child psychology and psychiatry, and allied disciplines · 2023Article
- Early exposure to flame retardants is prospectively associated with anxiety symptoms in adolescents: A prospective birth cohort study.Depression and anxiety · 2022Article
- Neural response to monetary and social feedback demonstrates differential associations with depression and social anxiety.Social cognitive and affective neuroscience · 2021Article
- Like me Back: Neural Correlates of Low Perceived Relational Value in Peer Victimized Youth.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2021Article
- Emotional distractors and attentional control in anxious youth: eye tracking and fMRI data.Cognition & emotion · 2021Article
- Research Review: Pediatric anxiety disorders - what have we learnt in the last 10 years?Journal of child psychology and psychiatry, and allied disciplines · 2021Review
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Social anxiety disorder typically begins in adolescence, a sensitive period for brain development, when increased complexity and salience of peer relationships requires novel forms of social learning. Disordered social learning in adolescence may explain how brain dysfunction promotes social anxiety. Socially anxious adolescents (n = 15) and adults (n = 19) and non-anxious adolescents (n = 24) and adults (n = 32) predicted, then received, social feedback from high and low-value peers while undergoing functional magnetic resonance imaging (fMRI). A surprise recall task assessed memory biases for feedback. Neural correlates of social evaluation prediction errors (PEs) were assessed by comparing engagement to expected and unexpected positive and negative feedback. For socially anxious adolescents, but not adults or healthy participants of either age group, PEs elicited heightened striatal activity and negative fronto-striatal functional connectivity. This occurred selectively to unexpected positive feedback from high-value peers and corresponded with impaired memory for social feedback. While impaired memory also occurred in socially-anxious adults, this impairment was unrelated to brain-based PE activity. Thus, social anxiety in adolescence may relate to altered neural correlates of PEs that contribute to impaired learning about social feedback. Small samples necessitate replication. Nevertheless, results suggest that the relationship between learning and fronto-striatal function may attenuate as development progresses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.