Evidence map›Paper›PMID 25933377›Full record

ArticlePloS one2015

Effect of active case finding on prevalence and transmission of pulmonary tuberculosis in Dhaka Central Jail, Bangladesh.

Sayera Banu, Md Toufiq Rahman, Mohammad Khaja Mafij Uddin, Razia Khatun, Md Siddiqur Rahman Khan, Md Mojibur Rahman, Syed Iftekhar Uddin, Tahmeed Ahmed, James D Heffelfinger

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In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Number needed to screen for TB in clinical, structural or occupational risk groups.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Pooled it
  4. Review
  5. Article
  6. Review
  7. Spatial distribution of TB among individuals with a history of incarceration.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  8. Treatment as prevention and other interventions to reduce transmission of multidrug-resistant tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sayera BanuInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Md Toufiq RahmanInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Mohammad Khaja Mafij UddinInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Razia KhatunInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Md Siddiqur Rahman KhanInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Md Mojibur RahmanNational TB Control Program, Directorate General of Health Services, Mohakhali, Dhaka, Bangladesh.
Syed Iftekhar UddinDirectorate of Prisons, Nazimuddin Road, Dhaka, Bangladesh.
Tahmeed AhmedInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
James D HeffelfingerInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh; Global Disease Detection Branch, Division of Global Health Protection, Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding tuberculosis (TB) transmission dynamics is essential for establishing effective TB control strategies in settings where the burden and risk of transmission are high. The objectives of this study were to evaluate the effect of active screening on controlling TB transmission and also to characterize Mycobacterium tuberculosis strains for investigating transmission dynamics in a correctional setting.

methodsThe study was carried out in Dhaka Central Jail (DCJ), from October 2005 to February 2010. An active case finding strategy for pulmonary TB was established both at the entry point to the prison and inside the prison. Three sputum specimens were collected from all pulmonary TB suspects and subjected to smear microscopy, culture, and drug susceptibility testing as well as genotyping which included deletion analysis, spoligotyping and analysis of mycobacterial interspersed repetitive units (MIRU).

resultsA total of 60,585 inmates were screened during the study period. We found 466 inmates with pulmonary TB of whom 357 (77%) had positive smear microscopy results and 109 (23%) had negative smear microscopy results but had positive results on culture. The number of pulmonary TB cases declined significantly, from 49 cases during the first quarter to 8 cases in the final quarter of the study period (p=0.001). Deletion analysis identified all isolates as M. tuberculosis and further identified 229 (70%) strains as 'modern' and 100 (30%) strains as 'ancestral'. Analysis of MIRU showed that 347 strains (85%) exhibited unique patterns, whereas 61 strains (15%) clustered into 22 groups. The largest cluster comprised eight strains of the Beijing M. tuberculosis type. The rate of recent transmission was estimated to be 9.6%.

conclusionsImplementation of active screening for TB was associated with a decline in TB cases in DCJ. Implementation of active screening in prison settings might substantially reduce the national burden of TB in Bangladesh.

Indexed as

Bacterial Typing TechniquesBangladeshHumansMycobacterium tuberculosisPhylogenyPrevalencePrisonersPrisonsTuberculosis, Pulmonary

Identifiers

PMID25933377
PMCPMC4416744

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.