Evidence map›Paper›PMID 25933186›Full record

ArticleHuman vaccines & immunotherapeutics2015

Incidence of Epstein-Barr virus in Syrian women with breast cancer: A tissue microarray study.

Tahar Aboulkassim, Amber Yasmeen, Nizar Akil, Gerald Batist, Ala-Eddin Al Moustafa

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  5. Epstein-Barr Viral Infection and the Risk for Breast Cancer: A Systematic Review.International journal of hematology-oncology and stem cell research · 2023
    Review
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  13. Prevalence of Epstein-Barr virus (EBV) in Iranian Breast Carcinoma Patients.Asian Pacific journal of cancer prevention : APJCP · 2020
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tahar Aboulkassima Segal Cancer Center ; Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis-Jewish General Hospital ; McGill University ; Montreal , Quebec , Canada.
Amber Yasmeen
Nizar Akil
Gerald Batist
Ala-Eddin Al Moustafa
Jewish General Hospital · CASyrian Center for Tobacco Studies · SYUniversity of Aleppo · SY

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Epstein-Barr virus (EBV) has been recently shown to be present in human breast cancer worldwide, which could play an important role in the initiation and progression of this cancer. In this regard, we aimed to explore the prevalence of EBV in 108 breast cancer tissues from Syrian women using polymerase chain reaction (PCR) and tissue microarray (TMA) analysis. We found that EBV is present in 56 (51.85%) of breast cancers samples. Additionally, we report that the expression of LMP1 gene of EBV is associated with a cancer invasive phenotype in the majority of the cancer samples. These data imply that EBV is present in breast cancer worldwide including Syria and its presence is associated with more aggressive cancer phenotype. Thus, future investigations are needed to elucidate the exact role of EBV in breast carcinogenesis and metastasis.

Indexed as

AdultAgedBreast NeoplasmsDNA, ViralFemaleHerpesvirus 4, HumanHumansIncidenceMiddle AgedPolymerase Chain ReactionSyriaTissue Array AnalysisDNA, Viralbreast cancerEpstein–Barr virusinvasive cancerSyrian women

Identifiers

PMID25933186
PMCPMC4514243
OpenAlexW1588074297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.