ArticlePloS one2015
Cerebrovascular Diseases in Workers at Mayak PA: The Difference in Radiation Risk between Incidence and Mortality.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Radiation and circulatory disease.Mutation research. Reviews in mutation researchPooled it
- Cohort Studies and Multi-omics Approaches to Low-Dose Ionizing Radiation-Induced Cardiovascular Disease: A Comprehensive Review.Cardiovascular toxicology · 2025Review
- Revisiting an Inverse Dose-Fractionation Effect of Ionizing Radiation Exposure for Ischemic Heart Disease: Insights from Recent Studies.Radiation research · 2024Review
- Circulatory disease mortality among male medical radiation workers in South Korea, 1996-2019.Scandinavian journal of work, environment & health · 2023Article
- Incidence risks for cerebrovascular diseases and types of stroke in a cohort of Mayak PA workers.Radiation and environmental biophysics · 2022Article
- Epidemiology of stroke and transient ischemic attacks in the population of the territories adjacent to the former Semipalatinsk Nuclear Test Site, Kazakhstan.Radiation and environmental biophysics · 2022Article
- Low- and moderate-dose non-cancer effects of ionizing radiation in directly exposed individuals, especially circulatory and ocular diseases: a review of the epidemiology.International journal of radiation biology · 2021Review
- Ionizing radiation-induced circulatory and metabolic diseases.Environment international · 2021Review
- ProZES: the methodology and software tool for assessment of assigned share of radiation in probability of cancer occurrence.Radiation and environmental biophysics · 2020Article
- Dose limits for occupational exposure to ionising radiation and genotoxic carcinogens: a German perspective.Radiation and environmental biophysics · 2020Review
- Radio-biologically motivated modeling of radiation risks of mortality from ischemic heart diseases in the Canadian fluoroscopy cohort study.Radiation and environmental biophysics · 2020Article
- Dose-responses for mortality from cerebrovascular and heart diseases in atomic bomb survivors: 1950-2003.Radiation and environmental biophysics · 2018Article
- Mortality from Circulatory Diseases and other Non-Cancer Outcomes among Nuclear Workers in France, the United Kingdom and the United States (INWORKS).Radiation research · 2017Article
- A mechanistic model for atherosclerosis and its application to the cohort of Mayak workers.PloS one · 2017Article
- Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure (Review).International journal of molecular medicine · 2016Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A detailed analysis of cerebrovascular diseases (CeVD) for the cohort of workers at Mayak Production Association (PA) is presented. This cohort is especially suitable for the analysis of radiation induced circulatory diseases, due to the detailed medical surveillance and information on several risk factors. The risk after external, typically protracted, gamma exposure is analysed, accounting for potential additional internal alpha exposure. Three different endpoints have been investigated: incidence and mortality from all cerebrovascular diseases and incidence of stroke. Particular emphasis was given to the form of the dose-response relationship and the time dependence of the radiation induced risk. Young attained age was observed to be an important, aggravating modifier of radiation risk for incidence of CeVD and stroke. For incidence of CeVD, our analysis supports a dose response sub-linear for low doses. Finally, the excess relative risk per dose was confirmed to be significantly higher for incidence of CeVD compared to CeVD mortality and incidence of stroke. Arguments are presented for this difference to be based on a true biological effect.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.