Observational studyNursing research
Neighborhood socioeconomic status during childhood versus puberty in relation to endogenous sex hormone levels in adult women.
Observational study in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neighborhood walkability and sex steroid hormone levels in women.Environmental research · 2022Pooled it
- Hormonal Medication Effects on Trichotillomania and Skin Picking Disorder.Life (Basel, Switzerland) · 2026Article
- Signs of Potential Androgen Excess Across the Lifespan in a US-based Digital Cohort Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort.BMJ open · 2025Article
- Timing, duration, and differential susceptibility to early life adversities and cardiovascular disease risk across the lifespan: Implications for future research.Preventive medicine · 2021Review
- Early Life Adversity and Pubertal Timing: Implications for Cardiometabolic Health.Journal of pediatric psychology · 2021Article
- Targeting Parenting Quality to Reduce Early Life Adversity Impacts on Lifespan Cardiometabolic Risk.Frontiers in psychology · 2021Review
- Social Determinants of Cardiovascular Health: Early Life Adversity as a Contributor to Disparities in Cardiovascular Diseases.The Journal of pediatrics · 2020Article
- A model of neglect during postnatal life heightens obesity-induced hypertension and is linked to a greater metabolic compromise in female mice.International journal of obesity (2005) · 2018Article
- Race disparities in pubertal timing: Implications for cardiovascular disease risk among African American women.Population research and policy review · 2017Article
- Sex-specific effects of stress on metabolic and cardiovascular disease: are women at higher risk?American journal of physiology. Regulatory, integrative and comparative physiology · 2017Review
- Postnatal treatment with metyrapone attenuates the effects of diet-induced obesity in female rats exposed to early-life stress.American journal of physiology. Endocrinology and metabolism · 2017Article
- Neighborhood-Level Poverty at Menarche and Prepregnancy Obesity in African-American Women.Journal of pregnancy · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundSocioeconomic adversity in early life is related to cardiovascular risk in adulthood; however, no studies have examined whether such adversity may be related to endogenous sex hormones, which are themselves associated with cardiovascular outcomes, or whether the timing of adversity exposures (childhood vs. puberty) matters.
objectiveThe goal of the current study was to separately examine neighborhood socioeconomic status (SES) during periods of childhood and puberty in relation to adulthood levels of endogenous sex hormones (estradiol [E2], testosterone), sex hormone binding globulin (SHBG), and a derived index of bioavailable testosterone (free androgen index).
methodsIn a sample of 143 premenopausal women (mean age = 36.8 [SD = 5.5]; 51.7% White, 32.2% African American, 5.6% Latina, 7.0% Chinese, and 3.5% Filipina), retrospective reports of residential address information in designated periods of childhood and puberty were used to derive U.S. census-based neighborhood SES composite scores characterizing the socioeconomic environments of women during these periods.
resultsIn covariate-adjusted analyses, higher neighborhood SES in puberty predicted higher levels of SHBG in adulthood, but neighborhood SES during childhood did not (standardized regression coefficient = .24, p = .01 vs. standardized regression coefficient = .04, p = .75, respectively). Neighborhood SES was not predictive of other hormones (E2, testosterone, and free androgen index). DISCUSSION: The current findings suggest that puberty may be a time of particular vulnerability to the effects of neighborhood SES on SHBG levels, which have been linked to cardiovascular risk factor profiles and atherosclerotic disease progression.
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