ArticlePloS one2015
Use of medications and lifestyles of hypertensive patients with high risk of cardiovascular disease in rural China.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Trial
- Process Evaluation of a Clustered Randomized Control Trial of a Comprehensive Intervention to Reduce the Risk of Cardiovascular Events in Primary Health Care in Rural China.International journal of environmental research and public health · 2020Trial
- Trial
- Associations between social determinants and poor hypertension treatment adherence among middle-aged and older people in rural China: a hospital-based case‒control study.BMC public health · 2026Article
- Exploring challenges to medication adherence aacmong young and middle-aged adults with coronary heart disease in China: a qualitative study.Frontiers in cardiovascular medicine · 2025Article
- The Association of Midday Napping With Hypertension Among Chinese Adults Older Than 45 Years: Cross-sectional Study.JMIR public health and surveillance · 2022Article
- Dawning public health services dogma: An indigenous Southwest Chinese perspective in managing hypertension-with or without the "BPHS"?Frontiers in public health · 2022Article
- Potential Impact of the 2017 High Blood Pressure Guideline Beyond the United States: A Case Study of the People's Republic of China.American journal of hypertension · 2020Article
- Decentralising NCD management in rural southern Africa: evaluation of a pilot implementation study.BMC public health · 2020Article
- Comparing the income-related inequity of tested prevalence and self-reported prevalence of hypertension in China.International journal for equity in health · 2018Article
- Changes of the perceived quality of care for older patients with hypertension by community health centers in shanghai.BMC family practice · 2017Article
- Relationships between urinary electrolytes excretion and central hemodynamics, and arterial stiffness in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension, with a global prevalence of 40%, is a risk factor for cardiovascular diseases (CVD). We conducted an exploratory study in Zhejiang China to understand the prevention of CVD among hypertensive patients with a 10 year CVD risk of 20% or higher. We assessed current practices in a rural 'township hospital' (a primary care facility), and compared them with international evidence-based practice.
methodsA questionnaire survey was conducted to examine the use of modern drugs (antihypertensive drugs, statins and aspirin) and traditional drugs, compliance to medications and lifestyle among 274 hypertensive patients aged 40-74, with a CVD risk of 20% or higher (using the Asian Equation).
resultsThe majority (72%) were diagnosed with hypertension at township hospitals. Only 15% of study participants used two anti-hypertensive drugs, 0.7% took statin and 2.9% aspirin. Only 2.9% combined two types of modern drugs, while 0.4% combined three types (antihypertensives, statins and aspirin). Herbal compounds, sometimes with internationally rarely recommended drugs such as Reserpine were taken by 44%. Analysis of drug adherence showed that 9.8% had discontinued their drug therapy by themselves. 16% had missed doses and these were on less anti-hypertensive drugs than those who did not (t=-5.217, P=0.003). Of all participants, 28% currently smoked, 39% drank regularly and only 21% exercised frequently. The average salt intake per day was 7.1 (±3.8) g, while the national recommended level is 6g.
conclusionThe study revealed outdated and inadequate treatment and health education for hypertensive patients, especially for those who have high risk scores for CVD. There is a need to review the community-based guidelines for hypertension management. Health providers and patients should make a transition from solely treating hypertension, towards prevention of CVD. Health system issues need addressing including improving rural health insurance cover and primary care doctors' capacity to manage chronic disease patients.
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