ArticleInternational journal of clinical and experimental medicine2015
Could pretreatment with oral contraceptives before pituitary down regulation reduce the incidence of ovarian hyperstimulation syndrome in the IVF/ICSI procedure?
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
- Effect of metformin and oral contraceptives on polycystic ovary syndrome and IVF cycles.Journal of endocrinological investigation · 2017Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
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Abstract
The long gonadotrophin releasing-hormone agonists (GnRH-a) protocol of pituitary down regulation was widely used in controlled ovarian hyperstimulation (COH). Some clinicians prefer to use one cycle of oral contraceptives (OC) pretreatment before the traditional long GnRH-a protocol. This study was aimed to investigate whether such pretreatment could reduce the incidence of ovarian hyperstimulation syndrome (OHSS) for patients with different ovarian responses in IVF/ICSI treatment. Participants undergoing IVF/ICSI treatment with long GnRH-a protocol of pituitary down regulation in luteal phase were recruited by their potential risk of OHSS into one group of suspected high responders (227 participants) and the other group of suspected normal responders (665 participants). As for the suspected high responders, pretreatment with OC could lower the serum LH level, LH/FSH ratio and E2 level right after 14 days of pituitary down regulation. It could also lower the serum E2 level before oocytes retrieval and the count of oocytes collected. The incidence of severe OHSS was also significantly decreased. Such effect of OC on hormone profile, follicular dynamics and incidence of OHSS was not discovered in the group of suspected normal responders.
Indexed as
Identifiers
25932224PMC4402871W1854386547What OpenQuestion holds
Registered trials
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