ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015
Desmoplastic infantile astrocytoma with multiple intracranial and intraspinal localizations at presentation.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Suprasellar Desmoplastic Infantile Ganglioglioma in a 7-Month-Old Infant: A Rare Diagnostic Consideration in Infant Suprasellar Masses.Clinical case reports · 2026Article
- Desmoplastic infantile astrocytoma with atypical phenotype, PTEN homozygous deletion and BRAF V600E mutation.Acta neuropathologica communications · 2022Article
- Desmoplastic infantile astrocytoma and ganglioglioma: a series of 12 patients treated at a single institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Multifocal Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIA/DIG): An Institutional Series Report and a Clinical Summary of This Rare Tumor.Frontiers in oncology · 2021Article
- Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: a single institution's experience.Journal of neurosurgery. Pediatrics · 2018Article
- A Rare Tumor in Childhood Desmoplastic Infantile Astrocytoma: Two Case Reports.Sisli Etfal Hastanesi tip bulteni · 2018Article
- Desmoplastic astrocytoma: new insights into its clinical profile, diagnosis, and treatment.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Multiple desmoplastic infantile gliomas--therapeutic challenges.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Multiple desmoplastic astrocytoma: a benign neoplasm?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Desmoplastic infantile ganglioglioma/astrocytoma: Expanding the molecular and morphological spectrum with a novel BRAF fusion.Neuro-oncology advancesArticle
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeDesmoplastic infantile gliomas (DIG) are rare tumors that occur in infants aged between 1 and 24 months. The tumor in general has a favorable prognosis after surgical resection. There are no treatment algorithms, however, for patients with multiple intracranial and intraspinal presentations. CASE REPORT: In an 11-month-old girl with a history of nystagmus, magnetic resonance imaging (MRI) demonstrated contrast-enhancing lesions in the suprasellar region, the cerebellar vermis, and the spinal axis. The tumor in the cerebellar vermis was removed via a suboccipital midline approach. The histological examination revealed a desmoplastic infantile astrocytoma (DIA) WHO grade I. Postoperatively, it was decided to adopt a wait-and-see strategy. Further development, up to 16 months after surgery, was unremarkable. Follow-up MRI showed no recurrence of the posterior fossa tumor, mild progress of the suprasellar tumor, and significant regression of the spinal tumors.
conclusionDIA is a rare mostly benign brain tumor found in infants. The final diagnosis always relies on histology. Surgical resection is the recommended therapy for symptomatic tumors; however, more experience is needed to develop treatment recommendations for multiple-site tumors.
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