Evidence map›Paper›PMID 25930035›Full record

ReviewBMC infectious diseases2015

How to treat fungal infections in ICU patients.

Dimitrios K Matthaiou, Theodora Christodoulopoulou, George Dimopoulos

Open access · goldAbstract readReview
In one paragraph

Review in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Retrospective Evaluation of Risk Factors for InvasiveInfectious diseases & clinical microbiology · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. In Vitro Antifungal Activity and Mechanism of AgMolecules (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Frontiers in microbiology · 2018
    Review
  14. Article
  15. Encapsulation of Antifungals in Micelles ProtectsFrontiers in microbiology · 2017
    Article
  16. Article
  17. Lactoferrin, chitosan and Melaleuca alternifolia-natural products that show promise in candidiasis treatment.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dimitrios K MatthaiouDepartment of Critical Care, University Hospital ATTIKON, Medical School, University of Athens, 1 Rimini str, Haidari-Athens, 12462, Greece. d.matthaiou@gmail.com.
Theodora ChristodoulopoulouDepartment of Critical Care, University Hospital ATTIKON, Medical School, University of Athens, 1 Rimini str, Haidari-Athens, 12462, Greece. dorachristodoulopoulou@yahoo.gr.
George DimopoulosDepartment of Critical Care, University Hospital ATTIKON, Medical School, University of Athens, 1 Rimini str, Haidari-Athens, 12462, Greece. gdimop@med.uoa.gr.
National and Kapodistrian University of Athens · GRUniversity General Hospital Attikon · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections represent a major burden in the critical care setting with increasing morbidity and mortality. Candidiasis is the leading cause of such infections, with C. albicans being the most common causative agent, followed by Aspergillosis and Mucormycosis. The diagnosis of such infections is cumbersome requiring increased clinical vigilance and extensive laboratory testing, including radiology, cultures, biopsies and other indirect methods. However, it is not uncommon for definitive evidence to be unavailable. Risk and host factors indicating the probability of infections may greatly help in the diagnostic approach. Timely and adequate intervention is important for their successful treatment. The available therapeutic armamentarium, although not very extensive, is effective with low resistance rates for the newer antifungal agents. However, timely and prudent use is necessary to maximize favorable outcomes.

Indexed as

Practice Patterns, Physicians'Antifungal AgentsAspergillosisCandidiasisHospitalizationHumansIntensive Care UnitsMucormycosisMycosesAntifungal Agents

Identifiers

PMID25930035
PMCPMC4419464
OpenAlexW2029107623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.