ArticleJournal of applied physiology (Bethesda, Md. : 1985)2015
Heat acclimation improves heat exercise tolerance and heat dissipation in individuals with extensive skin grafts.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Exercise and Heat Stress in Well-Healed Burn Survivors: Effects of Cooling Modalities on Thermal and Perceptual Responses.Medicine and science in sports and exercise · 2025Trial
- Efficacy of water spray for evaporative cooling in athletes with spinal cord injury.Spinal cord series and cases · 2019Trial
- β-Adrenergic blockade does not impair the skin blood flow sensitivity to local heating in burned and nonburned skin under neutral and hot environments in children.Microcirculation (New York, N.Y. : 1994) · 2017Trial
- Effect of burn injury size on cardiovascular responses to exercise in the heat.European journal of applied physiology · 2025Article
- Burn size and environmental conditions modify thermoregulatory responses to exercise in burn survivors.Journal of burn care & research : official publication of the American Burn Association · 2024Article
- Attrition of Well-Healed Burn Survivors to a 6-Month Community-Based Exercise Program: A Retrospective Evaluation.Journal of burn care & research : official publication of the American Burn Association · 2023Article
- Key Exercise Concepts in the Rehabilitation from Severe Burns.Physical medicine and rehabilitation clinics of North America · 2023Review
- Evidence for Chronotropic Incompetence in Well-healed Burn Survivors.Journal of burn care & research : official publication of the American Burn Association · 2023Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Edward F. Adolph Distinguished Lecture. It's more than skin deep: thermoregulatory and cardiovascular consequences of severe burn injuries in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Rehabilitative Exercise Training for Burn Injury.Sports medicine (Auckland, N.Z.) · 2021Review
- Correlation of neurological level and sweating level of injury in persons with spinal cord injury.The journal of spinal cord medicine · 2021Observational
- Exercise Thermoregulation with a Simulated Burn Injury: Impact of Air Temperature.Medicine and science in sports and exercise · 2020Article
- Exercise Core Temperature Response with a Simulated Burn Injury: Effect of Body Size.Medicine and science in sports and exercise · 2020Article
- Impact of passive heat stress on persons with spinal cord injury: Implications for Olympic spectators.Temperature (Austin, Tex.) · 2019Review
- Post Junctional Sudomotor and Cutaneous Vascular Responses in Noninjured Skin Following Heat Acclimation in Burn Survivors.Journal of burn care & research : official publication of the American Burn AssociationArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Burn survivors with extensive skin grafts have impaired heat dissipation and thus heat tolerance. This study tested the hypothesis that heat acclimation (HA) improves these factors in this population. Thirty-four burn survivors were stratified into highly [>40% body surface area (BSA) grafted, n = 15] and moderately (17-40% BSA grafted, n = 19) grafted groups. Nine healthy nonburned subjects served as controls. Subjects underwent 7 days of HA involving 90 min of exercise at ∼ 50% peak oxygen uptake in 40°C, 30% relative humidity. On days 1 and 7, subjects exercised in the heat at a fixed rate of metabolic heat production. Pre-HA, all controls and 18/19 subjects in the 17-40% group completed 90 min of exercise. Conversely, heat exercise tolerance was lower (P < 0.01) in the > 40% group, with 7/15 subjects not completing 90 min of exercise. Post-HA, heat exercise tolerance was similar between groups (P = 0.39) as all subjects, except one, completed 90 min of exercise. Pre-HA, the magnitude of the increase in internal temperature during exercise occurred sequentially (P ≤ 0.03) according to BSA grafted (>40%: 1.6 ± 0.5°C; 17-40%: 1.2 ± 0.3°C; control: 0.9 ± 0.2°C). HA attenuated (P < 0.01) increases in internal temperature in the control (by 0.2 ± 0.3°C), 17-40% (by 0.3 ± 0.3°C), and > 40% (by 0.3 ± 0.4°C) groups, the magnitude of which was similar between groups (P = 0.42). These data indicate that HA improves heat tolerance and dissipation in burn survivors with grafted skin, and the magnitude of these improvements are not influenced by the extent of skin grafting.
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