ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2015
Nutraceuticals: Definition and Epidemiological Rationale for Their Use in Clinical Practice.
Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- LDL-cholesterol lowering effect of a new dietary supplement: an open label, controlled, randomized, cross-over clinical trial in patients with mild-to-moderate hypercholesterolemia.Lipids in health and disease · 2018Trial
- Nutraceutical Effects on Glucose and Lipid Metabolism in Patients with Impaired Fasting Glucose: A Pilot, Double-Blind, Placebo-Controlled, Randomized Clinical Trial on a Combined Product.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017Trial
- Effects of a Combined Nutraceutical on Lipid Pattern, Glucose Metabolism and Inflammatory Parameters in Moderately Hypercholesterolemic Subjects: A Double-blind, Cross-over, Randomized Clinical Trial.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017Trial
- TG/HDL-c ratio as a predictor of progressive infarction in patients with anterior circulation single subcortical infarction.Brain and behavior · 2024Article
- The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension.Frontiers in cardiovascular medicine · 2024Review
- The Modulation of PCSK9 and LDLR by Supercritical COMolecules (Basel, Switzerland) · 2021Article
- Benchmarking Nutraceutical Soybean Composition Relative to Protein and Oil.Frontiers in nutrition · 2021Review
- Nutraceuticals in Chronic Coronary Syndromes: Preclinical Data and Translational Experiences.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Review
- Commentary to "The Possible Role of Nutraceuticals in the Prevention of Cardiovascular Disease".High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019Article
- Role of cholesterol and sphingolipids in brain development and neurological diseases.Lipids in health and disease · 2019Review
- Nutraceuticals: opening the debate for a regulatory framework.British journal of clinical pharmacology · 2018Review
- To Nutraceuticals and Back: Rethinking a Concept.Foods (Basel, Switzerland) · 2017Article
- Nutraceuticals in hypercholesterolaemia: an overview.British journal of pharmacology · 2017Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiometabolic risk factors, such as hypercholesterolemia, hypertriglyceridemia, metabolic syndrome, diabetes, and arterial hypertension, are major predictors of the premature development of cardiovascular diseases (CVD). Since CVD prevention needs a life-course approach, beyond dietary and pharmacological treatment, non-pharmacological treatment should be considered an important alternative for patients in primary prevention with mild-moderate cardiometabolic risk factors at low-moderate global risk of CVD. Several functional foods and nutraceuticals are efficacious, safe and well tolerated. However, only some (monacolins of red yeast rice and omega-3 fatty acids) have showed, in long-term randomized clinical trials, a reduction of cardiovascular events.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.