Evidence map›Paper›PMID 25929252›Full record

ArticleBMC pulmonary medicine2015

Predictors of microbial agents in dust and respiratory health in the Ecrhs.

Christina Tischer, Jan-Paul Zock, Maria Valkonen, Gert Doekes, Stefano Guerra, Dick Heederik, Deborah Jarvis, Dan Norbäck, Mario Olivieri, Jordi Sunyer and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Amelioration of Inflammation in Rats with Experimentally Induced Asthma byInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Direct-Read Fluorescence-Based Measurements of Bioaerosol Exposure in Home Healthcare.International journal of environmental research and public health · 2022
    Article
  7. Associations between Housing Factors and Respiratory Symptoms in Two Saskatchewan First Nations Communities.International journal of environmental research and public health · 2021
    Article
  8. Review
  9. Article
  10. Mold and Human Health: a Reality Check.Clinical reviews in allergy & immunology · 2017
    Review
  11. Article
  12. Article
  13. Application of the Environmental Relative Moldiness Index in Finland.Applied and environmental microbiology · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 8 countries.

Christina TischerInstitute of Epidemiology I, Helmholtz Zentrum München, Ingolstädter Landstrasse 1,German Research Centre for Environmental Health, D-85764, Neuherberg, Germany. ctischer@creal.cat.
Jan-Paul ZockCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. jpzock@creal.cat.
Maria ValkonenLiving Environment and Health Unit, National Institute for Health and Welfare, Kuopio, Finland. maria.valkonen@thl.fi.
Gert DoekesInstitute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands. G.Doekes@uu.nl.
Stefano GuerraCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. sguerra@creal.cat.
Dick HeederikInstitute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands. d.heederik@uu.nl.
Deborah JarvisRespiratory Epidemiology and Public Health Group, Imperial College London, London, UK. d.jarvis@imperial.ac.uk.
Dan NorbäckThe Department of Medical Science, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden. dan.norback@medsci.uu.se.
Mario OlivieriDepartment of Occupational Medicine, University of Verona, Verona, Italy. mario.olivieri@univr.it.
Jordi SunyerCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. jsunyer@creal.cat.
Cecilie SvanesDepartment of Occupational Medicine, Centre for International Health, University of Bergen and , Haukeland University Hospital, Bergen, Norway. cecilie.svanes@helse-bergen.no.
Martin TäubelLiving Environment and Health Unit, National Institute for Health and Welfare, Kuopio, Finland. martin.taubel@thl.fi.
Elisabeth ThieringInstitute of Epidemiology I, Helmholtz Zentrum München, Ingolstädter Landstrasse 1,German Research Centre for Environmental Health, D-85764, Neuherberg, Germany. elisabeth.thiering@helmholtz-muenchen.de.
Giuseppe VerlatoEpidemiology and Medical Statistics, University of Verona, Verona, Italy. giuseppe.verlato@univr.it.
Anne HyvärinenLiving Environment and Health Unit, National Institute for Health and Welfare, Kuopio, Finland. anne.hyvarinen@thl.fi.
Joachim HeinrichInstitute of Epidemiology I, Helmholtz Zentrum München, Ingolstädter Landstrasse 1,German Research Centre for Environmental Health, D-85764, Neuherberg, Germany. heinrich@helmholtz-muenchen.de.
Center for Research in Environmental Epidemiology · ESFinnish Institute for Health and Welfare · FIHelmholtz Zentrum München · DEUniversity of Verona · ITUtrecht University · NLHaukeland University Hospital · NOImperial College London · GBUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess predictors of microbial agents in mattress dust throughout Europe and to investigate associations between microbial exposures, home characteristics and respiratory health.

methodsSeven different fungal and bacterial parameters were assessed in mattress dust from 956 adult ECRHS II participants in addition to interview based home characteristics. Associations between microbial parameters and the asthma score and lung function were examined using mixed negative binomial regression and linear mixed models, respectively.

resultsIndoor dampness and pet keeping were significant predictors for higher microbial agent concentrations in mattress dust. Current mould and condensation in the bedroom were significantly associated with lung function decline and current mould at home was positively associated with the asthma score. Higher concentrations of muramic acid were associated with higher mean ratios of the asthma score (aMR 1.37, 95%CI 1.17-1.61). There was no evidence for any association between fungal and bacterial components and lung function.

conclusionIndoor dampness was associated with microbial levels in mattress dust which in turn was positively associated with asthma symptoms.

Indexed as

Air Pollution, IndoorHousingAdultAsthmaBacteriaBedsDustEuropeFemaleForced Expiratory VolumeFungiHumansLungMaleMuramic AcidsVital CapacityDustMuramic Acids

Identifiers

PMID25929252
PMCPMC4425915
OpenAlexW2153847765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.