Evidence map›Paper›PMID 25929246›Full record

ArticleChemical communications (Cambridge, England)2015

An in situ Raman spectroscopy-based microfluidic "lab-on-a-chip" platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms.

Jinsong Feng, César de la Fuente-Núñez, Michael J Trimble, Jie Xu, Robert E W Hancock, Xiaonan Lu

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Comparison of TwoMicroorganisms · 2021
    Article
  5. Review
  6. Testing Anti-Biofilm Polymeric Surfaces: Where to Start?International journal of molecular sciences · 2019
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinsong FengFood, Nutrition, and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada. xiaonan.lu@ubc.ca.
César de la Fuente-Núñez
Michael J Trimble
Jie Xu
Robert E W Hancock
Xiaonan Lu

Funding

Novel adjunctive therapy for drug resistant Gram-negative pathogensR33AI098701 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI HANCOCK, ROBERT ERNEST WILLIAM · 2014 to 2016
$788k
Novel adjunctive therapy for drug resistant Gram-negative pathogensR21AI098701 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI HANCOCK, ROBERT ERNEST WILLIAM · 2012 to 2013
$297k
Canadian Institutes of Health Research MOP-74493NIAID NIH HHS R21 AI098701NIAID NIH HHS R21AI098701NIAID NIH HHS R33 AI098701
6 · The paper itself

Abstract

Pseudomonas aeruginosa biofilm was cultivated and characterized in a microfluidic "lab-on-a-chip" platform coupled with confocal Raman microscopy in a non-destructive manner. Biofilm formation could be quantified by this label-free platform and correlated well with confocal laser scanning microscopy. This Raman-microfluidic platform could also discriminate biofilms at different developmental stages.

Indexed as

BiofilmsLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesMicroscopy, ConfocalPrincipal Component AnalysisPseudomonas aeruginosaSpectrum Analysis, Raman

Identifiers

PMID25929246
PMCPMC4433399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.