Evidence map›Paper›PMID 25928870›Full record

Trial reportTrials2015

Neurofeedback as a nonpharmacological treatment for adults with attention-deficit/hyperactivity disorder (ADHD): study protocol for a randomized controlled trial.

Kerstin Mayer, Sarah Nicole Wyckoff, Andreas J Fallgatter, Ann-Christine Ehlis, Ute Strehl

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04065906 (Near-infrared Spectroscopy Neurofeedback as a Treatment for Children With Attention Deficit Hyperactivity Disorder), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04065906 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Near-infrared Spectroscopy Neurofeedback as a Treatment for Children With Attention Deficit Hyperactivity Disorder

TypeinterventionalSponsorXijing HospitalRan2019 to 2020Enrolled90ConditionsNeurofeedback, Attention Deficit Hyperactivity Disorder (ADHD)ArmsNIRS neurofeedback, Methylphenidate or Tomoxetine
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kerstin MayerInstitute for Medical Psychology and Behavioral Neurobiology, University of Tübingen, Silcherstrasse 5, 72076, Tübingen, Germany. kerstin.mayer@uni-tuebingen.de.
Sarah Nicole WyckoffInstitute for Medical Psychology and Behavioral Neurobiology, University of Tübingen, Silcherstrasse 5, 72076, Tübingen, Germany. wyckoffsarah@gmail.com.
Andreas J FallgatterDepartment for Psychiatry and Psychotherapy, University of Tübingen, Osianderstr. 24, 72076, Tübingen, Germany. andreas.fallgatter@med.uni-tuebingen.de.
Ann-Christine EhlisDepartment for Psychiatry and Psychotherapy, University of Tübingen, Osianderstr. 24, 72076, Tübingen, Germany. ann-christine.ehlis@med.uni-tuebingen.de.
Ute StrehlInstitute for Medical Psychology and Behavioral Neurobiology, University of Tübingen, Silcherstrasse 5, 72076, Tübingen, Germany. ute.strehl@uni-tuebingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared spectroscopy (NIRS) on symptomatology and neurophysiological parameters in an adult ADHD population. A comparison of SCP and NIRS feedback therapy methods has not been previously conducted and may yield valuable findings about alternative treatments for adult ADHD. METHODS/

designThe outcome of both neurofeedback techniques will be assessed over 30 treatment sessions and after a 6-month follow-up period, and then will be compared to a nonspecific biofeedback treatment. Furthermore, to investigate if treatment effects in this proof-of-principle study can be predicted by specific neurophysiological baseline parameters, regression models will be applied. Finally, a comparison with healthy controls will be conducted to evaluate deviant pretraining neurophysiological parameters, stability of assessment measures, and treatment outcome. DISCUSSION: To date, an investigation and comparison of SCP and NIRS feedback training to an active control has not been conducted; therefore, we hope to gain valuable insights in effects and differences of these types of treatment for ADHD in adults.

trial registrationThis study is registered with the German Registry of Clinical Trials: DRKS00006767 , date of registration: 8 October 2014.

Indexed as

ElectromyographySpectroscopy, Near-InfraredAction PotentialsAdultAttention Deficit Disorder with HyperactivityCerebral CortexClinical ProtocolsGermanyHumansNeurofeedbackResearch DesignTime FactorsTreatment Outcome

Identifiers

PMID25928870
PMCPMC4433028

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.