Evidence map›Paper›PMID 25928057›Full record

ArticlePloS one2015

Genomic Characterizations of Six Pigeon Paramyxovirus Type 1 Viruses Isolated from Live Bird Markets in China during 2011 to 2013.

Jingjing Wang, Hualei Liu, Wei Liu, Dongxia Zheng, Yunling Zhao, Yin Li, Yingli Wang, Shengqiang Ge, Yan Lv, Yuanyuan Zuo and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

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  12. Review detection of Newcastle disease virus.Frontiers in veterinary science · 2022
    Review
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  16. AvianFrontiers in veterinary science · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jingjing WangOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Hualei LiuOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Wei LiuChina Animal Disease Control Center, Beijing 100125, China.
Dongxia ZhengOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Yunling ZhaoOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Yin LiDivision of Epidemiology Survey, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Yingli WangOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Shengqiang GeOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Yan LvOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Yuanyuan ZuoOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Songmei YuOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
Zhiliang WangOIE Reference Laboratory for Newcastle Disease, China Animal Health and Epidemiology Center, Qingdao 266032, China.
China Animal Health and Epidemiology Center · CNChina Animal Disease Control Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genomes of six pigeon paramyxovirus type 1 (PPMV-1) isolated from symptomless pigeons in live poultry markets during the national active surveillance from 2011 to 2013 were sequenced and analyzed in this study. The complete genome lengths of all isolates were 15,192 nucleotides with the gene order of 3'-NP-P-M-F-HN-L-5'. All isolates had the same motif of 112RRQKRF117 at the cleavage site of the fusion protein, which was typical of velogenic Newcastle disease virus (NDV). Several mutations were identified in the functional domains of F and HN proteins, including fusion peptide, heptad repeat region, transmembrane domains and neutralizing epitopes. Phylogenetic analysis based on sequences of complete genomes and six genes revealed that all isolates belonged to genotype VI in class II, but at least 2 sub-genotypes were identified. Most isolates were placed into sub-genotype VIb with the exception of pi/GX/1015/13, which was classified in sub-genotype VIa. The obvious antigenic difference between PPMV-1 isolates and La Sota strain was found based on the R-value calculated by cross hemagglutination inhibition (HI) assay. These results provided the evidence that PPMV-1 could be detected from healthy pigeons, and our study may be useful in designing vaccines used in pigeon, and developing molecular diagnostic tools to monitor and prevent future PPMV-1 outbreaks.

Indexed as

AnimalsBirdsGenome, ViralNewcastle disease virusPhylogeny

Identifiers

PMID25928057
PMCPMC4415766
OpenAlexW2021719674

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.