SynthesisScientific reports2015
Vasectomy and prostate cancer risk: a meta-analysis of cohort studies.
Synthesis in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Vasectomy and prostate cancer risk: a pooled of cohort studies and Mendelian randomization analysis.BMC cancer · 2025Pooled it
- Association between vasectomy and risk of prostate cancer: a meta-analysis.Prostate cancer and prostatic diseases · 2021Pooled it
- The Association Between Vasectomy and Prostate Cancer: A Systematic Review and Meta-analysis.JAMA internal medicine · 2017Pooled it
- Migraine and breast cancer risk: a meta-analysis of observational studies based on MOOSE compliant.Medicine · 2016Pooled it
- History of Vasectomy Is not Associated With Prostate Cancer Progression in Men on Active Surveillance.The Prostate · 2025Article
- The review of the long-term health risks associated with vasectomy.International journal of impotence research · 2025Review
- Epidemiology beyond its limits.Science advances · 2022Article
- Review of Vasectomy Complications and Safety Concerns.The world journal of men's health · 2021Review
- Impact of Vasectomy on the Development and Progression of Prostate Cancer: Preclinical Evidence.Cancers · 2020Article
- Article
- Opinions and Attitudes About Vasectomy of Married Couples Living in Turkey.American journal of men's health · 2017Article
- Vasectomy and risk of prostate cancer: population based matched cohort study.BMJ (Clinical research ed.) · 2016Article
- Vasectomy and prostate cancer risk: a historical synopsis of undulating false causality.Research and reports in urology · 2016Review
- Vasectomy: potential links to an increased risk of aggressive prostate cancer?Expert review of anticancer therapy · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some studies have suggested that vasectomy is associated with the increased risk of prostate cancer, however, this conclusion is not supported by all the published studies. In order to examine the relationship between vasectomy and prostate cancer risk, we conducted a meta-analysis of cohort studies to clarify this controversial association. PubMed and Medline were used to identify the cohort studies that reported the association of vasectomy with prostate cancer risk from 1980 to January 2015. Based on a random effects model, the RR and 95% CI were used to assess the combined risk. In total, 10 cohort studies involving more than 7027 cases and 429914 participants were included. There was no significant relationship between vasectomy and prostate cancer risk, the pooled RR (95%CI) was 1.11[0.98, 1.27] (P = 0.109). In subgroup-analysis, the relationship between vasectomy and prostate cancer risk was not significantly modified by the length of follow-up and population distribution except Americans. Omission of any single study had little effect on the pooled risk estimate. Little evidence of publication bias was found. In conclusion, our meta-analysis suggests that vasectomy is not associated with the increased risk of prostate cancer. More studies based on other populations including the Chinese are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.